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8/26/2014 1:51:00 PM | Browse: 997 | Download: 791
Publication Name World Journal of Gastroenterology
Manuscript ID 6771
Country/Territory Serbia
Received
2013-10-29 08:46
Peer-Review Started
2013-10-29 21:09
To Make the First Decision
2013-12-16 17:43
Return for Revision
2013-12-18 14:40
Revised
2014-01-05 03:36
Second Decision
2014-03-05 14:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-05 15:10
Articles in Press
2014-05-23 11:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-05-27 10:09
Publish the Manuscript Online
2014-06-27 10:37
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Topic Highlights
Article Title Clinical implications of hepatitis B virus mutations: Recent advances
Manuscript Source Invited Manuscript
All Author List Ivana Lazarevic
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Education, Science and Technological Development, Republic of Serbia 175073
Corresponding Author Ivana Lazarevic, MD, PhD, Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Dr Subotica 1, 11000 Belgrade, Serbia. ilazarevic@med.bg.ac.rs
Key Words Hepatitis B virus; Hepatitis B virus variability; Mutation; Drug resistance; Vaccine escape
Core Tip Understanding the frequencies and clinical implications of Hepatitis B virus (HBV) mutations may contribute to improvement of diagnostic procedures, more proper planning of immunization programs and creating the most efficient therapeutic protocols. This paper brings an overview and latest research results on the most important, clinically relevant, HBV mutations. The covered topics include mutations involved in vaccine-escape phenomenon, resistance to currently available antiviral drugs, development of “occult” hepatitis, hepatocellular carcinoma, fulminant hepatitis and hepatitis B e antigen-negative hepatitis, as well as the problem of these mutations in HBV/human immunodeficiency virus and HBV/hepatitis C virus co-infected patients.
Publish Date 2014-06-27 10:37
Citation Lazarevic I. Clinical implications of hepatitis B virus mutations: Recent advances. World J Gastroenterol 2014; 20(24): 7653-7664
URL http://www.wjgnet.com/1007-9327/full/v20/i24/7653.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i24.7653
Full Article (PDF) WJG-20-7653.pdf
Full Article (Word) WJG-20-7653.doc
Manuscript File 6771-Review.docx
Answering Reviewers 6771-Answering reviewers.pdf
Copyright License Agreement 6771-Copyright assignment.pdf
Peer-review Report 6771-Peer reviews.pdf
Scientific Editor Work List 6771-Scientific editor work list.doc