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11/10/2021 1:44:23 AM | Browse: 246 | Download: 386
Publication Name World Journal of Clinical Cases
Manuscript ID 68486
Country/Territory Japan
Received
2021-05-25 01:33
Peer-Review Started
2021-05-25 01:37
To Make the First Decision
Return for Revision
2021-07-05 02:47
Revised
2021-07-13 11:37
Second Decision
2021-09-22 03:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-23 07:15
Articles in Press
2021-09-23 07:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-11-03 01:49
Publish the Manuscript Online
2021-11-10 01:44
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Study
Article Title Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer
Manuscript Source Unsolicited Manuscript
All Author List Yu Hashimoto, Tetsuo Ajiki, Hiroaki Yanagimoto, Daisuke Tsugawa, Kenta Shinozaki, Hirochika Toyama, Masahiro Kido and Takumi Fukumoto
ORCID
Author(s) ORCID Number
Yu Hashimoto http://orcid.org/0000-0003-4830-9448
Tetsuo Ajiki http://orcid.org/0000-0002-5807-6716
Hiroaki Yanagimoto http://orcid.org/0000-0001-6493-4732
Daisuke Tsugawa http://orcid.org/0000-0001-7526-9563
Kenta Shinozaki http://orcid.org/0000-0002-2265-924X
Hirochika Toyama http://orcid.org/0000-0003-0360-8460
Masahiro Kido http://orcid.org/0000-0003-0353-4238
Takumi Fukumoto http://orcid.org/0000-0003-1592-4524
Funding Agency and Grant Number
Corresponding Author Tetsuo Ajiki, MD, Professor, Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. ajiki@med.kobe-u.ac.jp
Key Words Biliary tract cancer; Staging laparoscopy; Neutrophil-lymphocyte ratio; Modified Glasgow prognostic score; Carbohydrate antigen 19-9; Carcinoembryonic antigen
Core Tip This is a retrospective study to clarify the risk factors for occult metastasis in patients with biliary tract cancer (BTC). Radiological detection of small liver metastasis or peritoneal metastasis is difficult, and 11% BTC patients resulted in exploratory laparotomy in 7 years. Serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 levels, neutrophil-lymphocyte ratio and modified Glasgow prognostic score were significantly higher in the exploratory laparotomy group than in resected group. In these, CEA > 7 ng/mL and a combination of these factors were useful for predicting occult metastasis in BTC. Based on these factors, selective staging laparoscopy may reduce the rate of exploratory laparotomy.
Publish Date 2021-11-10 01:44
Citation Hashimoto Y, Ajiki T, Yanagimoto H, Tsugawa D, Shinozaki K, Toyama H, Kido M, Fukumoto T. Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer. World J Clin Cases 2021; 9(32): 9770-9782
URL https://www.wjgnet.com/2307-8960/full/v9/i32/9770.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i32.9770
Full Article (PDF) WJCC-9-9770.pdf
Full Article (Word) WJCC-9-9770.docx
Manuscript File 68486_Auto_Edited.docx
Answering Reviewers 68486-Answering reviewers.pdf
Audio Core Tip 68486-Audio core tip.mp3
Biostatistics Review Certificate 68486-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 68486-Conflict-of-interest statement.pdf
Copyright License Agreement 68486-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 68486-Institutional review board statement.pdf
Institutional Review Board Approval Form or Document 68486-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 68486-Language certificate.pdf
Peer-review Report 68486-Peer-review(s).pdf
Scientific Misconduct Check 68486-Bing-Liu M-2.png
Scientific Editor Work List 68486-Scientific editor work list.pdf