| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile: A pooled analysis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Mary M Barker, Francesco Zaccardi, Emer M Brady, Gaurav S Gulsin, Andrew P Hall, Joseph Henson, Zin Zin Htike, Kamlesh Khunti, Gerald P McCann, Emma L Redman, David R Webb, Emma G Wilmot, Tom Yates, Jian Yeo, Melanie J Davies and Jack A Sargeant |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research Programme |
NIHR201165 |
|
| Corresponding Author |
Jack A Sargeant, PhD, Research Associate, Diabetes Research Centre, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, United Kingdom. jack.sargeant@leicester.ac.uk |
| Key Words |
Type 2 diabetes mellitus; Early-onset adult type 2 diabetes; Age of onset; Cardiovascular risk; Young adults; Glycaemic control; Obesity |
| Core Tip |
The diagnosis of type 2 diabetes (T2D) in younger adults, an increasingly common public health issue, is associated with a higher risk of cardiovascular complications and mortality, which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age. This analysis demonstrates the adverse effect of younger diagnosis of T2D on cardiovascular risk factors, highlighting the need for targeted multifactorial age-appropriate interventions in order to improve the cardiovascular risk factor profile of younger adults with T2D and reduce their subsequent risk of cardiovascular complications and mortality. |
| Publish Date |
2022-03-15 14:23 |
| Citation |
Barker MM, Zaccardi F, Brady EM, Gulsin GS, Hall AP, Henson J, Htike ZZ, Khunti K, McCann GP, Redman EL, Webb DR, Wilmot EG, Yates T, Yeo J, Davies MJ, Sargeant JA. Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile: A pooled analysis. World J Diabetes 2022; 13(3): 260-271 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i3/260.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i3.260 |
