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8/20/2014 6:38:00 PM | Browse: 512 | Download: 395
Publication Name World Journal of Gastroenterology
Manuscript ID 6867
Country of Manuscript Source Romania
2013-10-29 16:57
Peer-Review Started
2013-10-30 19:23
To Make the First Decision
2014-01-09 16:51
Return for Revision
2014-01-12 17:43
2014-02-07 20:28
Second Decision
2014-04-09 09:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-09 10:59
Articles in Press
2014-05-23 10:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-07 09:12
Publish the Manuscript Online
2014-08-20 18:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Cancer stem cells: Involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics
Manuscript Source Invited Manuscript
All Author List Cristiana Pistol Tanase, Ana Iulia Neagu, Laura Georgiana Necula, Cristina Mambet, Ana-Maria Enciu, Bogdan Calenic, Maria Linda Cruceru and Radu Albulescu
Funding Agency and Grant Number
Funding Agency Grant Number
Grants POS CCE (in part) 685-152/2010
Corresponding author Cristiana Pistol Tanase, MD, PhD, Department of Biochemistry-Proteomics, Victor Babes National Institute of Pathology, no 99-101 Splaiul Independentei, 050096 sect 5 Bucharest, Romania. bioch@vbabes.ro
Keywords Cancer stem cells; Pancreatic cancer; Cancer stem cells signaling pathways; Targeted therapy; miRNA
Core Tip Pancreatic cancer is one of the most aggressive and lethal malignancies, despite remarkable progress in understanding pancreatic carcinogenesis and new therapeutic approaches. The presence of highly resistant cancer stem cells (CSCs) and the changes in their signaling pathways lead to drug resistance in pancreatic cancer. CSCs are considered responsible for tumor growth, invasion, metastasis and recurrence. CSC involvement in pancreatic cancer pathogenesis has also highlighted them as preferential targets for therapy. This review is an update of the results in two main fields of research in pancreatic cancer, pathogenesis and therapy, focused on the narrow perspective of CSCs.
Publish Date 2014-08-20 18:38
Citation Tanase CP, Neagu AI, Necula LG, Mambet C, Enciu AM, Calenic B, Cruceru ML, Albulescu R. Cancer stem cells: Involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics. World J Gastroenterol 2014; 20(31): 10790-10801
Url http://www.wjgnet.com/1007-9327/full/v20/i31/10790.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i31.10790
Full Article (PDF) WJG-20-10790.pdf
Full Article (Word) WJG-20-10790.doc
Manuscript File 6867-Review.docx
Answering Reviewers 6867-Answering reviewers.pdf
Copyright License Agreement 6867-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 6867-Language certificate.pdf
Peer-review Report 6867-Peer reviews.pdf
Scientific Editor Work List 6867-Scientific editor work list.doc