Publication Name	World Journal of Gastroenterology
Manuscript ID	6940
Country	Italy

Received	2013-10-30 19:40
Peer-Review Started	2013-11-01 12:06
To Make the First Decision	2013-12-16 18:12
Return for Revision	2013-12-18 09:55
Revised	2014-01-15 19:11
Second Decision	2014-04-16 11:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-16 12:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-14 17:10
Publish the Manuscript Online	2014-05-28 11:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Occult hepatitis B virus and hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Teresa Pollicino and Carlo Saitta
Funding Agency and Grant Number
Corresponding Author	Teresa Pollicino, MD, Department of Pediatric, Gynecologic, Microbiological, and Biomedical Sciences, University Hospital of Messina, Via Consolare Valeria, 98124 Messina, Italy. tpollicino@unime.it
Key Words	Hepatitis B virus; Hepatitis B virus surface antigen; Hepatitis B virus DNA; HBx protein; Hepatocellular carcinoma; Occult hepatitis B virus infection
Core Tip	Accumulating evidence indicates that occult hepatitis B virus (HBV) infection (OBI) is an important risk factor for hepatocellular carcinoma (HCC) development both in hepatitis C virus (HCV)-infected and HCV-negative patients with chronic liver disease. Data form humans and animal models have shown that OBI may contribute to hepatocellular transformation through the same direct and indirect mechanisms that subtend HCC development in overt HBV infection. In this review, we aimed at revising the current epidemiological, clinical and molecular data linking OBI to HCC development.
Publish Date	2014-05-28 11:45
Citation	Pollicino T, Saitta C. Occult hepatitis B virus and hepatocellular carcinoma. World J Gastroenterol 2014; 20(20): 5951-5961
URL	http://www.wjgnet.com/1007-9327/full/v20/i20/5951.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i20.5951

Full Article (PDF)	WJG-20-5951.pdf
Full Article (Word)	WJG-20-5951.doc
Manuscript File	6940-Review.docx
Answering Reviewers	6940-Answering reviewers.pdf
Copyright License Agreement	6940-Copyright assignment.pdf
Peer-review Report	6940-Peer reviewer(s).pdf
Scientific Editor Work List	6940-Scientific editor work list.doc