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7/7/2022 10:23:38 AM | Browse: 326 | Download: 877
Publication Name World Journal of Critical Care Medicine
Manuscript ID 69486
Country/Territory Spain
Received
2021-07-22 12:54
Peer-Review Started
2021-07-22 12:58
To Make the First Decision
Return for Revision
2021-11-11 08:47
Revised
2021-12-01 19:45
Second Decision
2022-05-16 03:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-05-17 04:49
Articles in Press
2022-05-17 04:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-06-02 00:31
Publish the Manuscript Online
2022-07-07 10:23
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Systematic Reviews
Article Title Immunomodulatory therapy for the management of critically ill patients with COVID-19: A narrative review
Manuscript Source Invited Manuscript
All Author List David Andaluz-Ojeda, Pablo Vidal-Cortes, Álvaro Aparisi Sanz, Borja Suberviola, Lorena Del Río Carbajo, Leonor Nogales Martín, Estefanía Prol Silva, Jorge Nieto del Olmo, José Barberán and Ivan Cusacovich
ORCID
Author(s) ORCID Number
David Andaluz-Ojeda http://orcid.org/0000-0001-8167-0871
Pablo Vidal-Cortes http://orcid.org/0000-0003-0225-9975
Álvaro Aparisi Sanz http://orcid.org/0000-0002-3230-6368
Borja Suberviola http://orcid.org/0000-0001-7681-3890
Lorena Del Río Carbajo http://orcid.org/0000-0002-1606-8785
Leonor Nogales Martín http://orcid.org/0000-0003-2736-3760
Estefanía Prol Silva http://orcid.org/0000-0002-4893-3075
Jorge Nieto del Olmo http://orcid.org/0000-0002-4304-7795
José Barberán http://orcid.org/0000-0002-8364-5765
Ivan Cusacovich http://orcid.org/0000-0002-4984-0639
Funding Agency and Grant Number
Corresponding Author David Andaluz-Ojeda, MD, PhD, Assistant Professor, Consultant Physician-Scientist, Department of Critical Care, Hospital Universitario HM Sanchinarro, Hospitales Madrid, Oña, 10, Madrid 28050, Spain. davidandaluz78@yahoo.es
Key Words COVID-19; Critically ill patients; Treatment; Immunomodulary drugs; Phenotype; Immunosupression
Core Tip Two years after the onset of the pandemic the search for the most appropriate treatment of coronavirus disease 2019 (COVID-19) continues. Few treatments have been evaluated in the context of critically ill patients with COVID-19 considering it in most clinical trials as a negative “end point” of the disease rather than a study subject. This fact makes it extremely difficult to establish degrees of recommendation regarding the different therapeutic options currently available. This review aims to summarize the immunopathogenesis and the current evidence regarding the different immunomodulatory strategies tested in critically ill patients with COVID-19. In addition, the presence of different immunophenotypes that in the future will serve as a basis for individualized treatments is demonstrated.
Publish Date 2022-07-07 10:23
Citation Andaluz-Ojeda D, Vidal-Cortes P, Aparisi Sanz Á, Suberviola B, Del Río Carbajo L, Nogales Martín L, Prol Silva E, Nieto del Olmo J, Barberán J, Cusacovich I. Immunomodulatory therapy for the management of critically ill patients with COVID-19: A narrative review. World J Crit Care Med 2022;11(4): 269-297
URL https://www.wjgnet.com/2220-3141/full/v11/i4/269.htm
DOI https://dx.doi.org/10.5492/wjccm.v11.i4.269
Full Article (PDF) WJCCM-11-269.pdf
Full Article (Word) WJCCM-11-269.docx
PRISMA 2009 Checklist 69486-PRISMA-2009-Checklist-revision.pdf
Manuscript File 69486_Auto_Edited-LS.docx
Answering Reviewers 69486-Answering reviewers.pdf
Audio Core Tip 69486-Audio core tip.mp3
Biostatistics Review Certificate 69486-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 69486-Conflict-of-interest statement.pdf
Copyright License Agreement 69486-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 69486-Language certificate.pdf
Peer-review Report 69486-Peer-review(s).pdf
Scientific Misconduct Check 69486-Bing-Wang JJ-2.png
Scientific Editor Work List 69486-Scientific editor work list.pdf