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8/23/2022 9:54:46 AM | Browse: 258 | Download: 448
Publication Name World Journal of Clinical Oncology
Manuscript ID 69987
Country/Territory China
Received
2021-08-02 01:47
Peer-Review Started
2021-08-02 01:51
To Make the First Decision
Return for Revision
2021-11-10 14:35
Revised
2021-12-23 14:22
Second Decision
2022-07-21 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-26 17:55
Articles in Press
2022-07-26 17:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-07-11 00:13
Typeset the Manuscript
2022-08-17 09:36
Publish the Manuscript Online
2022-08-23 09:54
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Clinical and Translational Research
Article Title Eight hub genes as potential biomarkers for breast cancer diagnosis and prognosis: A TCGA-based study
Manuscript Source Unsolicited Manuscript
All Author List Nan Liu, Guo-Duo Zhang, Ping Bai, Li Su, Hao Tian and Miao He
ORCID
Author(s) ORCID Number
Nan Liu http://orcid.org/0000-0003-1617-0138
Guo-Duo Zhang http://orcid.org/0000-0002-2088-4590
Ping Bai http://orcid.org/0000-0001-7863-452X
Li Su http://orcid.org/0000-0001-9590-3402
Hao Tian http://orcid.org/0000-0002-8606-6806
Miao He http://orcid.org/0000-0002-4889-7959
Funding Agency and Grant Number
Corresponding Author Hao Tian, MS, Surgeon, Department of Breast and Thyroid Surgery, Southwest Hospital, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China. tianhao_cmu@163.com
Key Words Breast cancer; Bioinformatics; Hub gene; The Cancer Genome Atlas; Protein-protein interaction
Core Tip This study identified 1317 DEGs related to the occurrence and development of breast cancer (BC), 165 DEGs related to prognosis, and 8 hub genes (MAD2L1, PLK1, SAA1, CCNB1, SHCBP1, KIF4A, ANLN, and ERCC6L). Each of these eight hub genes has different expression levels in BC and is significantly related to prognosis. The results of this study indicate that studying these DEGs may help provide a full understanding of the molecular mechanisms underlying BC pathogenesis and progression. Moreover, these hub genes may serve as potential prognostic markers and therapeutic targets, which provide a reference for more in-depth and extensive prospective clinical research.
Publish Date 2022-08-23 09:54
Citation Liu N, Zhang GD, Bai P, Su L, Tian H, He M. Eight hub genes as potential biomarkers for breast cancer diagnosis and prognosis: A TCGA-based study. World J Clin Oncol 2022; 28(32): 4493-4507
URL https://www.wjgnet.com/2218-4333/full/v13/i8/675.htm
DOI https://dx.doi.org/10.5306/wjco.v13.i8.675
Full Article (PDF) WJCO-13-675.pdf
Full Article (Word) WJCO-13-675.docx
Manuscript File 69987_Auto_Edited-LM.docx
Answering Reviewers 69987-Answering reviewers.pdf
Audio Core Tip 69987-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 69987-Conflict-of-interest statement.pdf
Copyright License Agreement 69987-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 69987-Language certificate.pdf
Supplementary Material 69987-Supplementary material.pdf
Peer-review Report 69987-Peer-review(s).pdf
Scientific Misconduct Check 69987-CrossCheck.png
Scientific Misconduct Check 69987-Bing-Gong ZM-2.png
Scientific Editor Work List 69987-Scientific editor work list.pdf