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8/26/2014 5:16:00 PM | Browse: 360 | Download: 216
Publication Name World Journal of Gastroenterology
Manuscript ID 7020
Country of Manuscript Source China
2013-11-02 10:17
Peer-Review Started
2013-11-02 19:33
To Make the First Decision
2013-12-16 18:03
Return for Revision
2013-12-17 13:54
2014-01-07 14:06
Second Decision
2014-01-20 18:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-20 19:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-01 10:45
Typeset the Manuscript
2014-05-02 21:47
Publish the Manuscript Online
2014-05-28 11:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Meta-Analysis
Article Title Prognostic and clinicopathological significance of glypican-3 overexpression in hepatocellular carcinoma: A meta-analysis
Manuscript Source Invited Manuscript
All Author List Jia Li, Jian-Zhi Gao, Jing-Li Du and Li-Xin Wei
Funding Agency and Grant Number
Corresponding author Li-Xin Wei, PhD, Department of Pathology, Chinese PLA General Hospital, Haidian District, 28 Fuxing Road, Beijing 100853, China. weilx301@263.net
Keywords Hepatocellular carcinoma; Glypican-3; Prognosis; Clinicopathological parameter; Meta-analysis
Core Tip Glypican-3 (GPC3) is known to be a specific and available molecular marker for the diagnosis of hepatocellular carcinoma (HCC). However, the prognostic value of GPC3 overexpression in patients with HCC is less researched and remains controversial. We performed the meta-analysis including six eligible studies and demonstrated that GPC3 overexpression was associated with poor overall survival and disease-free survival in HCC. We also found that GPC3 expression was closely related with tumor vascular invasion, hepatic cirrhosis, tumor grade and tumor stage in HCC.
Publish Date 2014-05-28 11:45
Citation Li J, Gao JZ, Du JL, Wei LX. Prognostic and clinicopathological significance of glypican-3 overexpression in hepatocellular carcinoma: A meta-analysis. World J Gastroenterol 2014; 20(20): 6336-6344
Url http://www.wjgnet.com/1007-9327/full/v20/i20/6336.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i20.6336
Full Article (PDF) WJG-20-6336.pdf
Full Article (Word) WJG-20-6336.doc
Manuscript File 7020-Review.doc
Answering Reviewers 7020-Answering reviewers.pdf
Copyright License Agreement 7020-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 7020-Language certificate.pdf
Peer-review Report 7020-Peer review(s).pdf
Scientific Editor Work List 7020-Scientific editor work list.doc