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8/29/2014 5:10:00 PM | Browse: 992 | Download: 793
Publication Name World Journal of Clinical Cases
Manuscript ID 7286
Country Lebanon
2013-11-12 15:20
Peer-Review Started
2013-11-13 14:12
To Make the First Decision
2013-12-02 11:37
Return for Revision
2013-12-13 14:34
2014-01-02 18:45
Second Decision
2014-02-20 20:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-02-20 20:14
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-03-12 20:55
Publish the Manuscript Online
2014-03-20 19:24
ISSN 2307-8960 (online)
Open Access
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Case Report
Article Title Homozygous factor Ⅴ Leiden mutation in type Ⅳ Ehlers-Danlos patient
Manuscript Source Invited Manuscript
All Author List Marwan Refaat, Mostafa Hotait and Brion Winston
Funding Agency and Grant Number
Corresponding Author Marwan Refaat, MD, FACC, FAHA, FHRS, FASE, FESC, FACP, Assistant Professor of Medicine, Department of Cardiology, American University Medical Center, Cairo St, Beirut 110 72020, Lebanon. mr48@aub.edu.lb
Key Words Ehlers-Danlos syndrome; Factor V Leiden; Platelets; Coagulopathy
Core Tip Hemostatic abnormalities that have already been described in Ehlers-Danlos syndrome patients include platelet abnormalities (release defects, ?-storage pool disease) as well as clotting factor deficiencies that increase the bleeding tendencies of patients. The coexistence of platelet ?-storage pool disease and factor Ⅴ Leiden mutation in our patient manifested as having aneurysms of the splenic, renal, hepatic, gastric, mesenteric arteries and diffuse aneurysms of the upper and lower extremities as well as bilateral lower extremity deep vein thromboses and pulmonary emboli. This propensity to both bleeding and clotting made the management of our patient challenging on this presentation with acute anterolateral myocardial infarction.
Publish Date 2014-03-20 19:24
Citation Refaat M, Hotait M, Winston B. Homozygous factor V Leiden mutation in type IV Ehlers-Danlos patient. World J Clin Cases 2014; 2(3): 75-77 Available from: URL: http://www.wjgnet.com/2307-8960/full/v2/i3/75.htm DOI: http://dx.doi.org/10.12998/wjcc.v2.i3.75
URL http://www.wjgnet.com/2307-8960/full/v2/i3/75.htm
DOI http://dx.doi.org/10.12998/wjcc.v2.i3.75
Full Article (PDF) wjcc-2-75.pdf
Full Article (Word) wjcc-2-75.doc
Manuscript File 7286-Review.doc
Answering Reviewers 7286-Answering reviewers.pdf
Copyright License Agreement 7286-Copyright assignment.pdf
Peer-review Report 7286-Peer reviews.pdf
Scientific Editor Work List 7286-Scientific editor work list.doc