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1/13/2022 11:55:40 AM | Browse: 26 | Download: 68
Publication Name World Journal of Gastroenterology
Manuscript ID 73407
Country/Territory China
2021-11-26 01:25
Peer-Review Started
2021-11-26 01:26
To Make the First Decision
Return for Revision
2021-12-12 05:08
2021-12-14 09:48
Second Decision
2022-01-10 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-10 22:05
Articles in Press
2022-01-10 22:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-11 10:04
Publish the Manuscript Online
2022-01-13 11:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Control Study
Article Title Microbiome changes in the gastric mucosa and gastric juice in different histological stages of Helicobacter pylori-negative gastric cancers
Manuscript Source Unsolicited Manuscript
All Author List Qing-Hua Sun, Jing Zhang, Yan-Yan Shi, Jing Zhang, Wei-Wei Fu and Shi-Gang Ding
Author(s) ORCID Number
Qing-Hua Sun http://orcid.org/0000-0001-5029-587X
Jing Zhang http://orcid.org/0000-0003-4992-1831
Yan-Yan Shi http://orcid.org/0000-0003-0247-371X
Jing Zhang http://orcid.org/0000-0003-0083-3865
Wei-Wei Fu http://orcid.org/0000-0003-3543-854X
Shi-Gang Ding http://orcid.org/0000-0002-0831-0965
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 81700496
National Natural Science Foundation of China No. 81870386
Peking University Medicine Fund of Fostering Young Scholars’ Scientific & Technological Innovation BMU2021PY002
Key laboratory for Helicobacter pylori infection and upper gastrointestinal diseases, Beijing Key Laboratory No.BZ0371
Corresponding Author Shi-Gang Ding, MD, Professor, Department of Gastroenterology, Peking University Third Hospital, 49 Huayuan North Rd, Beijing 100191, China. dingshigang222@163.com
Key Words Gastric mucosa; Gastric juice; Microbiota; Stomach neoplasms; Histological stages; 16s RNA gene sequencing
Core Tip The gastric microbiome profile of Helicobacter pylori-negative precancerous lesions is poorly understood. This is the first study, to our knowledge, to compare the microbiota differences between paired gastric mucosa and gastric juice at different stages of gastric neoplastic progression. The findings revealed that the bacterial community of gastric juice differed from that of the gastric mucosa and that Helicobacter pylori-negative gastric cancer and precancerous lesions have distinct bacterial taxa. Patients with intestinal metaplasia and dysplasia had similar gastric mucosa microbiota profiles, with Ralstonia and Rhodococcus being the most predominant genera, which could aid in prognosis prediction.
Publish Date 2022-01-13 11:55
Citation Sun QH, Zhang J, Shi YY, Zhang J, Fu WW, Ding SG. Microbiome changes in the gastric mucosa and gastric juice in different histological stages of Helicobacter pylori-negative gastric cancers. World J Gastroenterol 2022; 28(3): 365-380
URL https://www.wjgnet.com/1007-9327/full/v28/i3/365.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i3.365
Full Article (PDF) WJG-28-365.pdf
Full Article (Word) WJG-28-365.docx
Manuscript File 73407_Auto_Edited-LJH.docx
Answering Reviewers 73407-Answering reviewers.pdf
Audio Core Tip 73407-Audio core tip.m4a
Biostatistics Review Certificate 73407-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 73407-Conflict-of-interest statement.pdf
Copyright License Agreement 73407-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 73407-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 73407-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 73407-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 73407-Language certificate.pdf
Supplementary Material 73407-Supplementary material.pdf
Peer-review Report 73407-Peer-review(s).pdf
Scientific Misconduct Check 73407-Bing-Liu JH-2.png
Scientific Misconduct Check 73407-CrossCheck.png
Scientific Editor Work List 73407-Scientific editor work list.pdf