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8/12/2022 11:48:45 AM | Browse: 276 | Download: 479
Publication Name World Journal of Diabetes
Manuscript ID 74142
Country/Territory Malaysia
Received
2021-12-15 00:53
Peer-Review Started
2021-12-15 00:55
To Make the First Decision
Return for Revision
2022-01-12 00:44
Revised
2022-01-24 16:51
Second Decision
2022-07-13 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-18 00:05
Articles in Press
2022-07-18 00:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-06-03 22:06
Typeset the Manuscript
2022-08-07 14:15
Publish the Manuscript Online
2022-08-12 11:48
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Basic Study
Article Title Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats
Manuscript Source Invited Manuscript
All Author List Nabilah Ibnat, Rahela Zaman, Mohammad Borhan Uddin, Ezharul Chowdhury and Chooi Yeng Lee
ORCID
Author(s) ORCID Number
Nabilah Ibnat http://orcid.org/0000-0002-7018-4867
Rahela Zaman http://orcid.org/0000-0002-8249-7668
Mohammad Borhan Uddin http://orcid.org/0000-0003-4384-4900
Ezharul Chowdhury http://orcid.org/0000-0002-5705-841X
Chooi Yeng Lee http://orcid.org/0000-0001-5847-0329
Funding Agency and Grant Number
Funding Agency Grant Number
FRGS grant from the Ministry of Education, Malaysia FRGS/2/2014/SG05/MUSM/03/1
Corresponding Author Chooi Yeng Lee, PhD, Senior Lecturer, School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Subang Jaya 47500, Selangor, Malaysia. chooi.yeng.lee@monash.edu
Key Words Glucagon-like peptide-1; Metabolic syndrome; Nanoparticles; Plasma half-life; Rat
Core Tip Glucagon-like peptide-1 (GLP1), owing to its physiological properties, is a promising peptide in the treatment of obesity and diabetes. Due to the short half-life of GLP1 and in order to improve GLP1 therapeutic use, GLP1 receptor agonists (GLP1-RAs) have been widely synthesised and encapsulated into nanocarriers for targeted delivery. But the use of GLP1-RAs is associated with unwanted side effects and risks. In the present study, we synthesised a new nanocarrier for native GLP1 - the GLP1 carbonate apatite nanoparticles. The nanocarrier appears comparable if not significantly better than other GLP1 nanoparticles, which have shown promising features as therapeutic agents.
Publish Date 2022-08-12 11:48
Citation Ibnat N, Zaman R, Uddin MB, Chowdhury E, Lee CY. Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats. World J Diabetes 2022; 13(8): 613-621
URL https://www.wjgnet.com/1948-9358/full/v13/i8/613.htm
DOI https://dx.doi.org/10.4239/wjd.v13.i8.613
Full Article (PDF) WJD-13-613.pdf
Full Article (Word) WJD-13-613.docx
Manuscript File 74142_Auto_Edited-YXJW-FilipodiaCL-LS.docx
Answering Reviewers 74142-Answering reviewers.pdf
Audio Core Tip 74142-Audio core tip.wav
Biostatistics Review Certificate 74142-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 74142-Conflict-of-interest statement.pdf
Copyright License Agreement 74142-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 74142-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 74142-Language certificate.pdf
Peer-review Report 74142-Peer-review(s).pdf
Scientific Misconduct Check 74142-Bing-Wu YXJ-2.png
Scientific Editor Work List 74142-Scientific editor work list.pdf