| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Prospective Study |
| Article Title |
Relationship of quality of life with adolescent glycolipid metabolism disorder: A cohort study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Xiao-Hua Liang, Yang-Ling Ren, Xiao-Yue Liang, Jing-Yu Chen, Ping Qu and Xian Tang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Intelligent Medicine Research Project of Chongqing Medical University |
ZHYX202109 |
| The Major Health Project of Chongqing Science and Technology Bureau |
CSTC2021jscx-gksb-N0001 |
| Research and Innovation Team of Chongqing Medical University |
W0088 |
| Joint Medical Research Project of Chongqing Municipal Health Commission and Chongqing Science and Technology Bureau |
2020MSXM062 |
| National Key Research and Development Project of the Ministry of Science and Technology of the People's Republic of China |
2017YFC0211705 |
| Young Scientists Fund Program of the National Natural Science Foundation of China |
81502826 |
|
| Corresponding Author |
Xiao-Hua Liang, MD, PhD, Associate Research Scientist, Department of Clinical Epidemiology and Biostatistics, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Health and Nutrition, No. 136 2nd Street, Yuzhong District, Chongqing 400016, China. xiaohualiang@hospital.cqmu.edu.cn |
| Key Words |
Quality of life; Insulin resistance; Lipids; Metabolic abnormality |
| Core Tip |
Persistent abnormalities of glucose and lipid metabolism in childhood have a well-established association with adulthood cardiovascular diseases. Previous conclusions about the association between quality of life (QoL) and glycolipid metabolism disorder were almost all based on adults with type 2 diabetes or dyslipidaemia, whereas there is limited evidence for the association between QoL and glycolipid metabolism disorder in healthy children and adolescents. This study found that a poor QoL score was associated with increased insulin, triglyceride, and IR levels, and the association was more significant in males than in females. In addition, seven domains, four factors, and total QoL score were negatively associated with abnormalities in glucose and lipid metabolism. Measures to improve the QoL of adolescents are essential to reduce the prevalence of glycolipid metabolism disorder. |
| Publish Date |
2022-07-11 05:53 |
| Citation |
Liang XH, Ren YL, Liang XY, Chen JY, Qu P, Tang X. Relationship of quality of life with adolescent glycolipid metabolism disorder: A cohort study. World J Diabetes 2022; 13(7): 566-580 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i7/566.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i7.566 |
