BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/25/2022 8:33:35 AM | Browse: 275 | Download: 566
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 74352
Country/Territory United Kingdom
Received
2021-12-21 13:28
Peer-Review Started
2021-12-21 13:30
To Make the First Decision
Return for Revision
2022-03-14 08:59
Revised
2022-03-19 10:15
Second Decision
2022-04-12 01:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-04-21 18:18
Articles in Press
2022-04-21 18:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-05-11 14:51
Publish the Manuscript Online
2022-05-25 08:33
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Cohort Study
Article Title Para-aortic lymph node involvement should not be a contraindication to resection of pancreatic ductal adenocarcinoma
Manuscript Source Invited Manuscript
All Author List Rupaly Pande, Shafiq Chughtai, Manish Ahuja, Rachel Brown, David C Bartlett, Bobby V Dasari, Ravi Marudanayagam, Darius Mirza, Keith Roberts, John Isaac, Robert P Sutcliffe and Nikolaos A Chatzizacharias
ORCID
Author(s) ORCID Number
Rupaly Pande http://orcid.org/0000-0003-2346-373X
Shafiq Chughtai http://orcid.org/0000-0002-5726-6032
Manish Ahuja http://orcid.org/0000-0001-9242-5038
Rachel Brown http://orcid.org/0000-0001-5395-8456
David C Bartlett http://orcid.org/0000-0001-8564-9420
Bobby V Dasari http://orcid.org/0000-0003-2375-1141
Ravi Marudanayagam http://orcid.org/0000-0002-0640-3535
Darius Mirza http://orcid.org/0000-0002-7531-9089
Keith Roberts http://orcid.org/0000-0003-1799-9829
John Isaac http://orcid.org/0000-0002-7946-1277
Robert P Sutcliffe http://orcid.org/000-0002-1881-7655
Nikolaos A Chatzizacharias http://orcid.org/0000-0002-4864-189X
Funding Agency and Grant Number
Corresponding Author Nikolaos A Chatzizacharias, FACS, FRCS, MD, PhD, Surgeon, Department of Hepato-Pancreato-Biliary and Liver Transplant Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Birmingham B15 2GW, United Kingdom. chatzizacharias@gmail.com
Key Words Para-aortic lymph node; Pancreatectomy; Survival; Pancreatic adenocarcinoma; Chemotherapy; Lymph node sampling
Core Tip Currently there is no consensus on the prognostic significance of para-aortic lymph node (PALN) involvement in pancreatic ductal adenocarcinoma (PDAC), which is staged as metastatic disease (M1). Our study has demonstrated that patients with PALN involvement have comparable oncological outcomes, overall survival (OS) and disease free survival, to ones without PALN disease, when the appropriate treatment pathway is competed (surgery and chemotherapy). Multivariable risk analysis did not identify PALN involvement as an independent predictor for OS, while it doubled the risk of disease recurrence. Our data support that PALN involvement should not be considered a contraindication to resection for PDAC.
Publish Date 2022-05-25 08:33
Citation Pande R, Chughtai S, Ahuja M, Brown R, Bartlett DC, Dasari BV, Marudanayagam R, Mirza D, Roberts K, Isaac J, Sutcliffe RP, Chatzizacharias NA. Para-aortic lymph node involvement should not be a contraindication to resection of pancreatic ductal adenocarcinoma. World J Gastrointest Surg 2022; 14(5): 429-441
URL https://www.wjgnet.com/1948-9366/full/v14/i5/429.htm
DOI https://dx.doi.org/10.4240/wjgs.v14.i5.429
Full Article (PDF) WJGS-14-429.pdf
Full Article (Word) WJGS-14-429.docx
Manuscript File 74352_Auto_Edited.docx
Answering Reviewers 74352-Answering reviewers.pdf
Audio Core Tip 74352-Audio core tip.m4a
Biostatistics Review Certificate 74352-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 74352-Conflict-of-interest statement.pdf
Copyright License Agreement 74352-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 74352-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 74352-Institutional review board statement.pdf
Peer-review Report 74352-Peer-review(s).pdf
Scientific Misconduct Check 74352-CrossCheck.png
Scientific Misconduct Check 74352-Bing-Gong ZM-2.png
Scientific Editor Work List 74352-Scientific editor work list.pdf