Publication Name	World Journal of Hepatology
Manuscript ID	74384
Country	United States

Received	2021-12-22 06:40
Peer-Review Started	2021-12-22 06:42
To Make the First Decision
Return for Revision	2022-02-08 09:45
Revised	2022-02-20 02:42
Second Decision	2022-04-26 02:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-04-26 22:04
Articles in Press	2022-04-26 22:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-05-07 02:34
Publish the Manuscript Online	2022-05-24 10:35

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Emerging curative-intent minimally-invasive therapies for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Kylie E Zane, Paul B Nagib, Sajid Jalil, Khalid Mumtaz and Mina S Makary
ORCID	Author(s) ORCID Number Kylie E Zane http://orcid.org/0000-0002-0914-839X Paul B Nagib http://orcid.org/0000-0001-8538-3116 Sajid Jalil http://orcid.org/0000-0001-6123-153X Khalid Mumtaz http://orcid.org/0000-0001-7868-6514 Mina S Makary http://orcid.org/0000-0002-2498-7132
Funding Agency and Grant Number
Corresponding Author	Mina S Makary, MD, Assistant Professor, Attending Doctor, Director, Division of Vascular and Interventional Radiology, Department of Radiology, The Ohio State University Wexner Medical Center, 395 W. 12th Ave, 4th Floor, Columbus, OH 43210, United States. mina.makary@osumc.edu
Key Words	Hepatocellular carcinoma; Loco-regional therapy; Radiation segmentectomy; Transarterial radio-embolization; Ablation; Transarterial chemo-embolization; Curative intent
Core Tip	Accepted curative modalities for early hepatocellular carcinoma (HCC) include resection, liver transplant, and loco-regional therapies. In this manuscript, we review the curative-intent loco-regional therapies including recent evidence from the LEGACY study and DOSISPHERE trial demonstrating a curative role for transarterial radio-embolization in early HCC.
Publish Date	2022-05-24 10:35
Citation	Zane KE, Nagib PB, Jalil S, Mumtaz K, Makary MS. Emerging curative-intent minimally-invasive therapies for hepatocellular carcinoma. World J Hepatol 2022; 14(5): 885-895
URL	https://www.wjgnet.com/1948-5182/full/v14/i5/885.htm
DOI	https://dx.doi.org/10.4254/wjh.v14.i5.885

Full Article (PDF)	WJH-14-885.pdf
Full Article (Word)	WJH-14-885.docx
Manuscript File	74384_Auto_Edited-YJM.docx
Answering Reviewers	74384-Answering reviewers.pdf
Audio Core Tip	74384-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	74384-Conflict-of-interest statement.pdf
Copyright License Agreement	74384-Copyright license agreement.pdf
Peer-review Report	74384-Peer-review(s).pdf
Scientific Editor Work List	74384-Scientific editor work list.pdf