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8/3/2022 7:54:39 AM | Browse: 18 | Download: 27
Publication Name World Journal of Gastroenterology
Manuscript ID 74816
Country/Territory China
2022-01-14 15:42
Peer-Review Started
2022-01-14 15:42
To Make the First Decision
Return for Revision
2022-04-12 02:07
2022-04-26 16:53
Second Decision
2022-07-04 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-06 03:13
Articles in Press
2022-07-06 03:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-07-01 01:17
Typeset the Manuscript
2022-07-27 00:06
Publish the Manuscript Online
2022-08-03 07:54
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Basic Study
Article Title N-linked glycoproteomic profiling in esophageal squamous cell carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Qi-Wei Liu, Hao-Jie Ruan, Wei-Xia Chao, Meng-Xiang Li, Ye-Lin Jiao, Douglas G Ward, She-Gan Gao and Yi-Jun Qi
Author(s) ORCID Number
Qi-Wei Liu http://orcid.org/0000-0002-7874-4056
Hao-Jie Ruan http://orcid.org/0000-0002-3201-3864
Wei-Xia Chao http://orcid.org/0000-0003-0700-658X
Meng-Xiang Li http://orcid.org/0000-0002-6987-545X
Ye-Lin Jiao http://orcid.org/0000-0002-4920-0738
Douglas G Ward http://orcid.org/0000-0002-2328-1445
She-Gan Gao http://orcid.org/0000-0002-7720-8729
Yi-Jun Qi http://orcid.org/0000-0003-0239-5862
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81072039
National Natural Science Foundation of China 81872037
Corresponding Author Yi-Jun Qi, MD, PhD, Professor, Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment; Henan Key Laboratory of Cancer Epigenetics; Cancer Hospital, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, No. 29 Jinghua Road, Luoyang 471003, Henan Province, China. qiyijun@haust.edu.cn
Key Words Esophageal squamous cell carcinoma; N-linked glycoprotein; Post-translational modification; Lectin; Cathepsin D; Haptoglobin; 14-3-3ζ
Core Tip Comprehensive N-linked glycoproteome was profiled by two-dimensional gel electrophoresis-based and isobaric tags for relative and absolute quantification (iTRAQ) labeling-based mass spectrometry quantitation in parallel after N-linked glycoprotein enrichment by a tandem of multilectin affinity chromatography. The iTRAQ labeling-based quantitative proteomic profiling outperformed protein spot intensity quantification used by two-dimensional gel electrophoresis. A total of 411 N-linked glycoproteins were identified, including 128 up-regulated and 283 down-regulated glycoproteins with differential expression, which provide the scientific community with a dataset of glycoproteins associated with esophageal squamous cell carcinoma for in-depth investigation.
Publish Date 2022-08-03 07:54
Citation Liu QW, Ruan HJ, Chao WX, Li MX, Jiao YL, Ward DG, Gao SG, Qi YJ. N-linked glycoproteomic profiling in esophageal squamous cell carcinoma. World J Gastroenterol 2022; 28(29): 3869-3885
URL https://www.wjgnet.com/1007-9327/full/v28/i29/3869.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i29.3869
Full Article (PDF) WJG-28-3869.pdf
Full Article (Word) WJG-28-3869.docx
Manuscript File 74816_Auto_Edited-YJM_WangTQ-LS.docx
Answering Reviewers 74816-Answering reviewers.pdf
Audio Core Tip 74816-Audio core tip.m4a
Biostatistics Review Certificate 74816-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 74816-Conflict-of-interest statement.pdf
Copyright License Agreement 74816-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 74816-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 74816-Institutional review board statement.pdf
Supplementary Material 74816-Supplementary material.pdf
Peer-review Report 74816-Peer-review(s).pdf
Scientific Editor Work List 74816-Scientific editor work list.pdf