| Category |
Psychiatry |
| Manuscript Type |
Case Control Study |
| Article Title |
Cognitive inflexibility in Japanese adolescents and adults with autism spectrum disorders
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Yuka Yasuda, Ryota Hashimoto, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Satomi Umeda-Yano, Haruo Fujino and Masatoshi Takeda |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Japanese Ministry of Health, Labor and Welfare |
H22-seishin-ippan-001 |
| Japan Society for the Promotion of Science |
22390225 |
| Japan Society for the Promotion of Science |
25293250 |
| Japan Society for the Promotion of Science |
24591680 |
| Challenging Exploratory Research |
23659565 |
| Japanese Ministry of Education, Culture, Sports, Science and Technology |
25129704 |
| Priority Areas-Research on the Pathomechanisms of Brain Disorders |
18023045 |
| Japan Foundation for Neuroscience and Mental Health |
|
|
| Corresponding Author |
Ryota Hashimoto, MD, PhD, Associate Professor, Molecular Research Center for Children’s Mental Development, United Graduate School of Child Development, Osaka University, D3, 2-2, Yamadaoka, Suita, Osaka 5650871, Japan. hashimor@psy.med.osaka-u.ac.jp |
| Key Words |
Executive function; Autism spectrum disorders; Perseverative errors of Nelson type; Negative feedback; Wisconsin Card Sorting Test |
| Core Tip |
We investigated executive function (EF) in Japanese adolescents and adults with autism spectrum disorders (ASD) compared to strictly matched controls. EF was assessed using the Wisconsin Card Sorting Test. To exclude confounding factors, the participants were matched for gender, age, years of education, full-scale intelligence quotient (IQ), performance IQ, verbal IQ, and attention level. Symptoms were assessed by the Autism-Spectrum Quotient Japanese version. We confirm that Japanese adolescents and adults with ASD have cognitive inflexibility, as suggested by previous findings. Furthermore, the present study results also indicate that subjects with ASD may not use negative feedback effectively. |
| Publish Date |
2014-07-10 11:34 |
| Citation |
Yasuda Y, Hashimoto R, Ohi K, Yamamori H, Fujimoto M, Umeda-Yano S, Fujino H, Takeda M. Cognitive inflexibility in Japanese adolescents and adults with autism spectrum disorders. World J Psychiatr 2014; 4(2): 42-48 |
| URL |
http://www.wjgnet.com/2220-3206/full/v4/i2/42.htm |
| DOI |
http://dx.doi.org/10.5498/wjp.v4.i2.42 |
