| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Study |
| Article Title |
Impact of comorbid renal dysfunction in patients with hepatocellular carcinoma on long-term outcomes after curative resection
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuzuru Sakamoto, Shingo Shimada, Toshiya Kamiyama, Ko Sugiyama, Yoh Asahi, Akihisa Nagatsu, Tatsuya Orimo, Tatsuhiko Kakisaka, Hirofumi Kamachi, Yoichi M Ito and Akinobu Taketomi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shingo Shimada, MD, PhD, Surgeon, Department of Gastroenterological Surgery, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Hokkaido, Japan. shingoshimada1979@true.ocn.ne.jp |
| Key Words |
Hepatocellular carcinoma; Hepatectomy; Renal dysfunction; Estimated glomerular filtration rate |
| Core Tip |
This retrospective study revealed that comorbid renal dysfunction (RD) had a negligible impact on the prognosis of hepatocellular carcinoma patients who underwent curative hepatectomy with appropriate perioperative management, and close attention to severe chronic kidney disease is necessary to prevent postoperative bleeding and surgical site infection. Of particular interest is the finding that regardless of the degree of comorbid RD, the overall survival rate and recurrence-free survival rate were comparable, even when using a propensity model to exclude the influence of patient characteristics, liver function, and other causes of death. Moreover, no RD patient, even severe RD patients, received maintenance hemodialysis after hepatectomy. |
| Publish Date |
2022-07-27 07:51 |
| Citation |
Sakamoto Y, Shimada S, Kamiyama T, Sugiyama K, Asahi Y, Nagatsu A, Orimo T, Kakisaka T, Kamachi H, Ito YM, Taketomi A. Impact of comorbid renal dysfunction in patients with hepatocellular carcinoma on long-term outcomes after curative resection. World J Gastrointest Surg 2022; 14(7): 670-684 |
| URL |
https://www.wjgnet.com/1948-9366/full/v14/i7/670.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v14.i7.670 |
