Publication Name	World Journal of Gastroenterology
Manuscript ID	7547
Country	China

Received	2013-11-24 11:52
Peer-Review Started	2013-11-24 14:30
To Make the First Decision	2013-12-04 08:39
Return for Revision	2013-12-06 08:00
Revised	2013-12-15 11:08
Second Decision	2014-01-15 20:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-15 20:34
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-01 13:28
Typeset the Manuscript	2014-05-03 21:16
Publish the Manuscript Online	2014-05-28 11:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	No association of G-protein beta polypeptide 3 polymorphism with irritable bowel syndrome: Evidence from a meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Zhi-Gang Pan, Chen Xiao and Dong-Xing Su
Funding Agency and Grant Number
Corresponding Author	Dr. Dong-Xing Su, Department of Gastroenterology, the Third Affiliated Hospital of Guangxi Medical University, 13 Dancun Road, Nanning 530031, Guangxi Zhuang Autonomous Region, China. 553851548@qq.com
Key Words	Irritable bowel syndrome; G-protein beta polypeptide 3; Polymorphisms; Meta-analysis
Core Tip	G-protein beta polypeptide 3 (GNB3) polymorphisms have been identified as an independent risk factor causally associated with functional gastrointestinal disorder and receive extensive interest. However, their association with irritable bowel syndrome (IBS) remains controversial. In the present paper, the authors combined the data from seven case-control studies with 1085 IBS cases and 1695 controls, and found that there were associations between GNB3 C825T polymorphism and IBS risk in the overall population; subgroup analysis did not reveal significant associations either in Asian population or Caucasian population. In regard to the subtypes of IBS (constipation-dominant type, diarrhea-dominant type and mixed type), no associations were found either.
Publish Date	2014-05-28 11:45
Citation	Pan ZG, Xiao C, Su DX. No association of G-protein beta polypeptide 3 polymorphism with irritable bowel syndrome: Evidence from a meta-analysis. World J Gastroenterol 2014; 20(20): 6345-6352
URL	http://www.wjgnet.com/1007-9327/full/v20/i20/6345.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i20.6345

Full Article (PDF)	WJG-20-6345.pdf
Full Article (Word)	WJG-20-6345.doc
Manuscript File	7547-Review.docx
Answering Reviewers	7547-Answering reviews.pdf
Copyright License Agreement	7547-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7547-Language certificate.pdf
Peer-review Report	7547-Peer review(s).pdf
Scientific Editor Work List	7547-Scientific editor work list.doc