| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Minireviews |
| Article Title |
COVID-19 neuropsychiatric repercussions: Current evidence on the subject
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ronaldo Teixeira da Silva Júnior, Jonathan Santos Apolonio, Beatriz Rocha Cuzzuol, Bruna Teixeira da Costa, Camilo Santana Silva, Glauber Rocha Lima Araújo, Marcel Silva Luz, Hanna Santos Marques, Luana Kauany de Sá Santos, Samuel Luca Rocha Pinheiro, Vinícius Lima de Souza Gonçalves, Mariana Santos Calmon and Fabrício Freire de Melo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Fabrício Freire de Melo, MSc, PhD, Postdoc, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Vitória da Conquista 45029094, Brazil. freiremelo@yahoo.com.br |
| Key Words |
SARS-CoV-2; COVID-19; Central nervous system; Quarantine; Neurologic disorders; Mental disorders |
| Core Tip |
Severe acute respiratory syndrome coronavirus 2 infection may also involve neurological and psychiatric manifestations, both by the viral action itself and by social distancing and quarantine. Headache, dizziness, cerebrovascular disorders, olfactory and gustatory dysfunction, neuromuscular abnormalities, anxiety, depression, and post-traumatic stress disorder may occur in this setting. Supporting these repercussions, this virus is able to reach the central nervous system by the interaction between the angiotensin-converting enzyme 2 and the transmembrane protease serine 2 expressed in the host nerve cells, and the viral spike glycoprotein. Finally, the management of these patients is complex and we review current evidence on the subject. |
| Publish Date |
2022-09-16 10:39 |
| Citation |
da Silva Júnior RT, Santos Apolonio J, Cuzzuol BR, da Costa BT, Silva CS, Araújo GRL, Silva Luz M, Marques HS, Santos LKS, Pinheiro SLR, Lima de Souza Gonçalves V, Calmon MS, Freire de Melo F. COVID-19 neuropsychiatric repercussions: Current evidence on the subject. World J Methodol 2022; 12(5): 365-380 |
| URL |
https://www.wjgnet.com/2222-0682/full/v12/i5/365.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v12.i5.365 |
