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7/11/2022 5:53:38 AM | Browse: 169 | Download: 278
Publication Name World Journal of Diabetes
Manuscript ID 76309
Country/Territory India
Received
2022-03-11 14:44
Peer-Review Started
2022-03-11 14:46
To Make the First Decision
Return for Revision
2022-04-18 00:29
Revised
2022-04-19 09:11
Second Decision
2022-06-10 03:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-17 22:32
Articles in Press
2022-06-17 22:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-05-28 01:01
Typeset the Manuscript
2022-07-05 13:26
Publish the Manuscript Online
2022-07-11 05:53
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Editorial
Article Title Renin-angiotensin system blockers-SGLT2 inhibitors-mineralocorticoid receptor antagonists in diabetic kidney disease: A tale of the past two decades!
Manuscript Source Invited Manuscript
All Author List Awadhesh Kumar Singh and Ritu Singh
ORCID
Author(s) ORCID Number
Awadhesh Kumar Singh http://orcid.org/0000-0002-8374-4536
Ritu Singh http://orcid.org/0000-0003-1779-0638
Funding Agency and Grant Number
Corresponding Author Awadhesh Kumar Singh, MBBS, MD, Consultant Physician-Scientist, Intermediate Editor, Senior Postdoctoral Fellow, Senior Researcher, Department of Diabetes & Endocrinology, G.D Hospital & Diabetes Institute, 133A, Lenin Sarani, Kolkata 700013, West Bengal, India. draksingh_2001@yahoo.com
Key Words Renin-angiotensin system blockers; SGLT-2 inhibitors; Mineralocorticoid receptor antagonist; Diabetic kidney disease; Chronic kidney disease; Renal outcomes; Cardiovascular outcomes
Core Tip Angiotensin receptor blockers were the first drug class to show a conclusive benefit in preventing diabetic kidney disease (DKD) progression through two randomized trials IDNT and RENAAL in 2001. Several newer pharmacological agents have been tested in DKD in the past 20 years without much success. Notably, recently conducted renal outcome trials of SGLT-2 inhibitors in patients with DKD such as CREDENCE, DAPA-CKD, and EMPA-KIDNEY have shown significant improvement in disease progression. Similarly, recent trials of the non-steroidal mineralocorticoid receptor antagonist finerenone (FIDELIO-DKD and FIGARO-DKD) have shown significant improvement in both renal and cardiac endpoints in DKD.
Publish Date 2022-07-11 05:53
Citation Singh AK, Singh R. Renin-angiotensin system blockers-SGLT2 inhibitors-mineralocorticoid receptor antagonists in diabetic kidney disease: A tale of the past two decades! World J Diabetes 2022; 13(7): 471-481
URL https://www.wjgnet.com/1948-9358/full/v13/i7/471.htm
DOI https://dx.doi.org/10.4239/wjd.v13.i7.471
Full Article (PDF) WJD-13-471.pdf
Full Article (Word) WJD-13-471.docx
Manuscript File 76309_Auto_Edited-FilipodiaCL-CKL-LS.docx
Answering Reviewers 76309-Answering reviewers.pdf
Audio Core Tip 76309-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 76309-Conflict-of-interest statement.pdf
Copyright License Agreement 76309-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 76309-Language certificate.pdf
Peer-review Report 76309-Peer-review(s).pdf
Scientific Misconduct Check 76309-Bing-Chang KL-2.jpg
Scientific Editor Work List 76309-Scientific editor work list.pdf