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9/9/2022 12:48:14 PM | Browse: 209 | Download: 316
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 76514
Country/Territory Chile
Received
2022-03-19 20:52
Peer-Review Started
2022-03-19 20:55
To Make the First Decision
Return for Revision
2022-05-12 03:21
Revised
2022-05-19 22:36
Second Decision
2022-08-09 02:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-10 04:27
Articles in Press
2022-08-10 04:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-08-26 01:39
Publish the Manuscript Online
2022-09-09 12:48
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Liquid biopsy to detect resistance mutations against anti-epidermal growth factor receptor therapy in metastatic colorectal cancer
Manuscript Source Invited Manuscript
All Author List Guillermo Valenzuela, Mauricio Burotto, Katherine Marcelain and Jaime González-Montero
ORCID
Author(s) ORCID Number
Guillermo Valenzuela http://orcid.org/0000-0002-8711-729X
Mauricio Burotto http://orcid.org/0000-0002-7150-4033
Katherine Marcelain http://orcid.org/0000-0003-4018-6623
Jaime González-Montero http://orcid.org/0000-0003-0324-2948
Funding Agency and Grant Number
Funding Agency Grant Number
Agencia Nacional de Investigación y Desarrollo de Chile, Fondo Nacional de Investigación en Salud (FONIS) SA20I0059
Corresponding Author Jaime González-Montero, MD, PhD, Assistant Professor, Department of Basic and Clinical Oncology, University of Chile, Independencia 1027, Casilla 70058, Santiago 8380453, Chile. jagonzalez@ug.uchile.cl
Key Words Colorectal neoplasms; Precision medicine; Liquid biopsy; Cetuximab; Panitumumab
Core Tip Contemporary management of metastatic colorectal cancer patients with wild type KRAS includes the use of anti-epidermal growth factor receptor (EGFR) agents, such as cetuximab or panitumumab, as first-line treatment. However, a significant number of patients receiving this treatment show disease progression. Some of the relapses could be explained by the presence of acquired resistance mutations in KRAS. Liquid biopsy of circulating tumor cells or circulating cell-free DNA is expected to improve the management of patients undergoing anti-EGFR therapy.
Publish Date 2022-09-09 12:48
Citation Valenzuela G, Burotto M, Marcelain K, González-Montero J. Liquid biopsy to detect resistance mutations against anti-epidermal growth factor receptor therapy in metastatic colorectal cancer. World J Gastrointest Oncol 2022; 14(9): 1654-1664
URL https://www.wjgnet.com/1948-5204/full/v14/i9/1654.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i9.1654
Full Article (PDF) WJGO-14-1654.pdf
Full Article (Word) WJGO-14-1654.docx
Manuscript File 76514_Auto_Edited-LM.docx
Answering Reviewers 76514-Answering reviewers.pdf
Audio Core Tip 76514-Audio core tip.wav
Conflict-of-Interest Disclosure Form 76514-Conflict-of-interest statement.pdf
Copyright License Agreement 76514-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 76514-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 76514-Language certificate.pdf
Peer-review Report 76514-Peer-review(s).pdf
Scientific Misconduct Check 76514-Bing-Fan JR-2.png
Scientific Editor Work List 76514-Scientific editor work list.pdf