| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Clinical Trial |
| Article Title |
Peroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication in esophageal achalasia: A single-center randomized controlled trial
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Eduardo Turiani Hourneaux de Moura, José Jukemura, Igor Braga Ribeiro, Galileu Ferreira Ayala Farias, Aureo Augusto de Almeida Delgado, Lara Meireles Azeredo Coutinho, Diogo Turiani Hourneaux de Moura, Rubens Antonio Aissar Sallum, Ary Nasi, Sergio A Sánchez-Luna, Paulo Sakai and Eduardo Guimarães Hourneaux de Moura |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Igor Braga Ribeiro, MD, PhD, Associate Research Scientist, Attending Doctor, Doctor, Research Scientist, Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de Sao Paulo, Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas HCFMUSP, Av. Dr Enéas de Carvalho Aguiar, 225, 6o Andar, Bloco 3, Cerqueira Cesar, Sao Paulo 05403-010 , Brazil. igorbraga1@gmail.com |
| Key Words |
Esophageal achalasia; Gastroesophageal reflux; Deglutition disorders; Heller myotomy; Fundoplication; Randomized controlled trial |
| Core Tip |
This randomized controlled trial aimed to compare the efficacy and outcomes of laparoscopic myotomy and partial fundoplication (LM-PF) with those of peroral endoscopic myotomy (POEM) in the treatment of patients with achalasia of any etiology. There were no statistically significant differences between the LM-PF and POEM groups regarding symptoms. However, the rates of reflux esophagitis were significantly higher in the POEM group. POEM and LM-PF appear to be equally effective in controlling the symptoms of achalasia, shortening length of hospital stay, and minimizing adverse events. However, POEM has the advantage of shortening anesthesia and procedure times. |
| Publish Date |
2022-08-31 11:27 |
| Citation |
de Moura ETH, Jukemura J, Ribeiro IB, Farias GFA, de Almeida Delgado AA, Coutinho LMA, de Moura DTH, Aissar Sallum RA, Nasi A, Sánchez-Luna SA, Sakai P, de Moura EGH. Peroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication in esophageal achalasia: A single-center randomized controlled trial. World J Gastroenterol 2022; 28(33): 4875-4889 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i33/4875.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i33.4875 |
