Publication Name	World Journal of Diabetes
Manuscript ID	77782
Country	China

Received	2022-06-06 00:51
Peer-Review Started	2022-06-06 00:53
To Make the First Decision
Return for Revision	2022-08-07 18:05
Revised	2022-08-19 05:47
Second Decision	2022-09-06 03:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-09-07 23:42
Articles in Press	2022-09-07 23:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-10-09 03:33
Publish the Manuscript Online	2022-10-14 08:30

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Clinical Trials Study
Article Title	Effectiveness and safety of human umbilical cord-mesenchymal stem cells for treating type 2 diabetes mellitus
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Fen Lian, Dong-Hui Lu, Hong-Li Liu, Yan-Jing Liu, Xiu-Qun Han, Yang Yang, Yuan Lin, Qing-Xiang Zeng, Zheng-Jie Huang, Feng Xie, Cai-Hao Huang, Hong-Mei Wu, Ai-Mei Long, Li-Ping Deng and Fan Zhang
ORCID	Author(s) ORCID Number Xiao-Fen Lian http://orcid.org/0000-0001-7950-8867 Dong-Hui Lu http://orcid.org/0000-0001-9172-2989 Hong-Li Liu http://orcid.org/0000-0002-2601-2857 Yan-Jing Liu http://orcid.org/0000-0003-0489-3769 Xiu-Qun Han http://orcid.org/0000-0001-9970-3416 Yang Yang http://orcid.org/0000-0002-1200-8072 Yuan Lin http://orcid.org/0000-0003-4623-2096 Qing-Xiang Zeng http://orcid.org/0000-0002-1551-3808 Zheng-Jie Huang http://orcid.org/0000-0001-8178-7957 Feng Xie http://orcid.org/0000-0002-6482-272X Cai-Hao Huang http://orcid.org/0000-0002-2116-9724 Hong-Mei Wu http://orcid.org/0000-0002-3054-0345 Ai-Mei Long http://orcid.org/0000-0002-4173-8445 Li-Ping Deng http://orcid.org/0000-0003-3981-6165 Fan Zhang http://orcid.org/0000-0001-5147-663X
Funding Agency and Grant Number	Funding Agency Grant Number Shenzhen Science and Technology Innovation Committee Projects JCYJ20170816105416349 Shenzhen High-level Hospital Construction Fund Shenzhen Key Medical Discipline Construction Fund SZXK010
Corresponding Author	Fan Zhang, MD, Doctor, Department of Endocrinology, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518000, Guangdong Province, China. bjdxszyynfm@163.com
Key Words	Type 2 diabetes; Human umbilical cord mesenchymal stem cells; Blood glucose; Homeostasis model assessment of β-cell function; Hypoglycemic agents
Core Tip	Our article focused on the effectiveness and safety of human umbilical cord mesenchymal stem cell (hUC-MSC) infusion for treating type 2 diabetes. The results suggest that hUC-MSC infusion can improve glycemia, restore islet β‑cell function, and reduce the dosage of hypoglycemic agents without serious adverse events.
Publish Date	2022-10-14 08:30
Citation	Lian XF, Lu DH, Liu HL, Liu YJ, Han XQ, Yang Y, Lin Y, Zeng QX, Huang ZJ, Xie F, Huang CH, Wu HM, Long AM, Zhang F. Effectiveness and safety of human umbilical cord-mesenchymal stem cells for treating type 2 diabetes mellitus. World J Diabetes 2022; 13(10): 877-887
URL	https://www.wjgnet.com/1948-9358/full/v13/i10/877.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i10.877

Full Article (PDF)	WJD-13-877.pdf
Full Article (Word)	WJD-13-877.docx
CONSORT 2010 Statement	77782-CONSORT-2010-Statement-revision.pdf
Manuscript File	77782_Auto_Edited-LS.docx
Answering Reviewers	77782-Answering reviewers.pdf
Audio Core Tip	77782-Audio core tip.mp3
Biostatistics Review Certificate	77782-Biostatistics statement.pdf
Clinical Trial Registration Statement	77782-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	77782-Conflict-of-interest statement.pdf
Copyright License Agreement	77782-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	77782-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	77782-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	77782-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	77782-Language certificate.pdf
Peer-review Report	77782-Peer-review(s).pdf
Scientific Editor Work List	77782-Scientific editor work list.pdf