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11/4/2022 5:24:37 AM | Browse: 192 | Download: 329
Publication Name World Journal of Gastroenterology
Manuscript ID 78916
Country/Territory Germany
Received
2022-07-28 05:56
Peer-Review Started
2022-07-28 05:59
To Make the First Decision
Return for Revision
2022-08-31 21:07
Revised
2022-09-17 07:39
Second Decision
2022-10-25 03:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-10-27 17:11
Articles in Press
2022-10-27 17:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-10-31 01:06
Publish the Manuscript Online
2022-11-04 05:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Esophageal Lichen Planus: Current Knowledge, Challenges and Future Perspectives
Manuscript Source Invited Manuscript
All Author List Annegrit Decker, Franziska Schauer, Adhara Lazaro, Carmen Monasterio, Arthur Robert Schmidt, Annette Schmitt-Graeff and Wolfgang Kreisel
ORCID
Author(s) ORCID Number
Annegrit Decker http://orcid.org/0000-0001-6413-8816
Adhara Lazaro http://orcid.org/0000-0001-9023-1387
Annette Schmitt-Graeff http://orcid.org/0000-0001-5082-7979
Wolfgang Kreisel http://orcid.org/0000-0001-6884-0135
Funding Agency and Grant Number
Corresponding Author Wolfgang Kreisel, MD, Emeritus Professor, Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases,, Faculty of Medicine, Medical Center - University of Freiburg, Hugstetter Str. 55, Freiburg 79106, Germany. wolfgang.kreisel@uniklinik-freiburg.de
Key Words Lichen planus; Esophagitis; T-lymphocytes; Budesonide; Dysphagia; Precancerosis
Core Tip Lichen planus is a frequent, chronic inflammatory disease involving the skin, mucous membranes and/or skin appendages. Esophageal involvement in lichen planus (ELP) is an underdiagnosed inflammatory condition. ELP mainly affects middle-aged women. The principal symptom is dysphagia. Aymptomatic cases may occur. An immune-mediated pathogenesis is probable. Endoscopy shows mucosal denudation and tearing, trachealization, and hyperkeratosis. Scarring esophageal stenosis occurs. Histology includes mucosal detachment, T-lymphocytic infiltrations, epithelial apoptosis, dyskeratosis, and hyperkeratosis. Direct immuno-fluorescence shows fibrinogen deposits along the basement membrane zone. Treatment with topical steroids or immunosuppression may induce symptomatic and histologic improvement. ELP can be regarded as a precancerous condition.
Publish Date 2022-11-04 05:24
Citation Decker A, Schauer F, Lazaro A, Monasterio C, Schmidt AR, Schmitt-Graeff A, Kreisel W. Esophageal lichen planus: Current knowledge, challenges and future perspectives. World J Gastroenterol 2022; 28(41): 5893-5909
URL https://www.wjgnet.com/1007-9327/full/v28/i41/5893.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i41.5893
Full Article (PDF) WJG-28-5893.pdf
Full Article (Word) WJG-28-5893.docx
Manuscript File 78916_Auto_Edited-LM.docx
Answering Reviewers 78916-Answering reviewers.pdf
Audio Core Tip 78916-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 78916-Conflict-of-interest statement.pdf
Copyright License Agreement 78916-Copyright license agreement.pdf
Peer-review Report 78916-Peer-review(s).pdf
Scientific Misconduct Check 78916-Bing-Liu GL-2.png
Scientific Misconduct Check 78916-Figures.zip
Scientific Editor Work List 78916-Scientific editor work list.pdf