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1/20/2023 1:48:21 PM | Browse: 35 | Download: 50
Publication Name World Journal of Gastroenterology
Manuscript ID 80210
Country/Territory Australia
Received
2022-09-20 04:15
Peer-Review Started
2022-09-20 04:19
To Make the First Decision
Return for Revision
2022-11-15 07:32
Revised
2022-12-19 04:40
Second Decision
2023-01-10 03:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-01-10 18:35
Articles in Press
2023-01-10 18:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-01-12 08:30
Publish the Manuscript Online
2023-01-20 13:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Gaseous metabolites as therapeutic targets in ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Chu K Yao and Chen Sarbagili-Shabat
ORCID
Author(s) ORCID Number
Chu K Yao http://orcid.org/0000-0002-5301-2457
Funding Agency and Grant Number
Corresponding Author Chu K Yao, PhD, RN, Senior Research Fellow, Department of Gastroenterology, Monash University, Level 6, Alfred Centre, 99 Commercial Road, Melbourne 3004, Australia. chu.yao@monash.edu
Key Words Diet; Ulcerative colitis; Hydrogen sulfide; Nitric oxide; Sulphide-reducing diet
Core Tip There is room to develop efficacious dietary therapies in ulcerative colitis (UC) by targeting underlying pathogenic mechanisms. Emerging data indicates that dietary factors play a significant role in modulating two gaseous metabolites, hydrogen sulphide and nitric oxide, that affect the integrity of the colonic mucosal barrier in UC. These gases are produced by the colonic microbiota in response to sulphur-containing protein and to a lesser extent, inorganic sulphur (sulphates and sulphites), but suppressed by the presence of fermentable fibre. Preliminary work suggests that a multi-prong diet that targets reduction of these gases have therapeutic potential and further randomised-controlled trials are underway.
Publish Date 2023-01-20 13:48
Citation Yao CK, Sarbagili-Shabat C. Gaseous metabolites as therapeutic targets in ulcerative colitis. World J Gastroenterol 2023; 29(4): 682-691
URL https://www.wjgnet.com/1007-9327/full/v29/i4/682.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i4.682
Full Article (PDF) WJG-29-682.pdf
Full Article (Word) WJG-29-682.docx
Manuscript File 80210_Auto_Edited-LM.docx
Answering Reviewers 80210-Answering reviewers.pdf
Audio Core Tip 80210-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 80210-Conflict-of-interest statement.pdf
Copyright License Agreement 80210-Copyright license agreement.pdf
Peer-review Report 80210-Peer-review(s).pdf
Scientific Misconduct Check 80210-Bing-Wang JJ-2.png
Scientific Editor Work List 80210-Scientific editor work list.pdf