Publication Name	World Journal of Diabetes
Manuscript ID	8034
Country	Netherlands

Received	2013-12-12 16:29
Peer-Review Started	2013-12-12 18:42
To Make the First Decision	2014-01-08 14:32
Return for Revision	2014-01-09 10:33
Revised
Second Decision	2014-03-14 18:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-14 18:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-11 10:14
Publish the Manuscript Online	2014-04-18 11:34

ISSN	1948-9358 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Nutrition & Dietetics
Manuscript Type	Review
Article Title	Chromium does not belong in the diabetes treatment arsenal: current evidence and future perspectives
Manuscript Source	Invited Manuscript
All Author List	Gijs WD Landman, Henk JG Bilo, Sebastiaan T Houweling and Nanne Kleefstra
Funding Agency and Grant Number
Corresponding Author	Gijs WD Landman, MD, PhD, Diabetes Centre, Isala, P.O. box 10400, 8000 GK Zwolle, The Netherlands. g.w.d.landman@isala.nl
Key Words	Chromium; Type 2 diabetes mellitus; Insulin resistance; Therapy; Supplements
Core Tip	In some patients who received prolonged parenteral nutrition, absence of trivalent chromium caused insulin resistance and diabetes and supplementation with trivalent chromium “cleared” this metabolic disease. The question is, whether chromium deficiency is a relevant factor in the cause of type 2 diabetes in general and whether supplementation with trivalent chromium can have beneficial effects in type 2 diabetes. Unfortunately, no reliable methods to estimate chromium status exists and according to current evidence, chromium does not improve glycemic control in patients with type 2 diabetes and patients should be advised not to take chromium supplements.
Publish Date	2014-04-18 11:34
Citation	Landman GWD, Bilo HJG, Houweling ST, Kleefstra N. Chromium does not belong in the diabetes treatment arsenal: current evidence and future perspectives. World J Diabetes 2014; 5(2): 160-164
URL	http://www.wjgnet.com/1948-9358/full/v5/i2/160.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i2.160

Full Article (PDF)	WJD-5-160.pdf
Full Article (Word)	WJD-5-160.doc
Manuscript File	8034-Review.doc
Answering Reviewers	8034-Language certificate.pdf
Copyright License Agreement	8034-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8034-Language certificate.pdf
Peer-review Report	8034-Peer review(s).pdf
Scientific Editor Work List	8034-Scientific editor work list.doc