Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	8049
Country

Received	2013-12-12 17:30
Peer-Review Started	2013-12-13 08:57
To Make the First Decision	2014-02-27 09:30
Return for Revision	2014-03-06 09:52
Revised	2014-04-24 09:47
Second Decision	2014-06-03 16:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-06-03 16:33
Articles in Press	2014-06-03 16:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-01 15:04
Publish the Manuscript Online	2014-09-04 09:25

ISSN	2150-5349 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pharmacology & Pharmacy
Manuscript Type	Review
Article Title	Pharmacological therapy of feed intolerance in the critically ills
Manuscript Source	Invited Manuscript
All Author List	Nam Q Nguyen
Funding Agency and Grant Number
Corresponding Author	Nam Q Nguyen, Associate Professor, Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, North Terrace, Adelaide, 5000 South Australia, Australia. quoc.nguyen@health.sa.gov.au
Key Words	Adverse effects; Critical illness; Enteral feeding; Feed intolerance; Prokinetic therapy
Core Tip	Feed intolerance during critical illness must be promptly recognized and treated due to the associated morbidity and mortality. The current first line treatment for feed intolerance is prokinetic therapy with erythromycin and metoclopramide (alone or in combination), which are highly effective and free of significant adverse effects. Although diarrhoea occurs commonly after combination prokinetic therapy, it is not associated with Clostridium difficile colitis and settled shortly after stopping the treatment. The use of prokinetic therapy over a long period or for prophylactic purpose, therefore, must be avoided and the indication for ongoing use of the drug(s) should be frequently reviewed.
Publish Date	2014-09-04 09:25
Citation	Nguyen NQ. Pharmacological therapy of feed intolerance in the critically ills. World J Gastrointest Pharmacol Ther 2014; 5(3): 148-155
URL	http://www.wjgnet.com/2150-5349/full/v5/i3/148.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v5.i3.148

Full Article (PDF)	WJGPT-5-148.pdf
Full Article (Word)	WJGPT-5-148.doc
Manuscript File	8049-Review.doc
Answering Reviewers	8049-Answering reviewers.pdf
Copyright License Agreement	8049-Copyright assignment.pdf
Peer-review Report	8049-Peer review(s).pdf
Scientific Misconduct Check	8049-CrossCheck.jpg
Scientific Editor Work List	8049-Scientific editor work list.pdf