| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology and Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Elevated calprotectin levels are associated with mortality in patients with acute decompensation of liver cirrhosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Camila Matiollo, Elayne Cristina de Morais Rateke, Emerita Quintina de Andrade Moura, Michelle Andrigueti, Fernanda Cristina de Augustinho, Tamara Liana Zocche, Telma Erotides Silva, Lenyta Oliveira Gomes, Mareni Rocha Farias, Janaina Luz Narciso-Schiavon and Leonardo Lucca Schiavon |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
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| Corresponding Author |
Leonardo Lucca Schiavon, PhD, Associate Professor, Department of Internal Medicine, Division of Gastroenterology, Federal University of Santa Catarina, Sao Paulo, Florianópolis 88040001, Santa Catarina, Brazil. leo-jf@uol.com.br |
| Key Words |
Inflammation; Liver cirrhosis; Acute-on-chronic liver failure |
| Core Tip |
Acute decompensation (AD) of cirrhosis is associated with systemic inflammation and increased circulating cytokines. In this context, inflammatory markers, such as calprotectin, may be of prognostic value. This prospective cohort study that included 200 subjects hospitalized for complications of cirrhosis, 20 outpatients with stable cirrhosis and 20 healthy controls. Serum calprotectin was associated with prognosis in patients with AD without acute-on-chronic liver failure and may be useful in clinical practice to early identify patients with a very low short-term survival. |
| Publish Date |
2022-11-24 12:34 |
| Citation |
Matiollo C, Rateke ECM, Moura EQA, Andrigueti M, Augustinho FC, Zocche TL, Silva TE, Gomes LO, Farias MR, Narciso-Schiavon JL, Schiavon LL. Elevated calprotectin levels are associated with mortality in patients with acute decompensation of liver cirrhosis. World J Hepatol 2022; 14(11): 1964-1976 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i11/1964.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i11.1964 |
