| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Local recurrence after successful endoscopic submucosal dissection for rectal mucinous mucosal adenocarcinoma: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuki Murakami, Hiroki Tanabe, Y. Ono, Yuya Sugiyama, Yu Kobayashi, Takehito Kunogi, Takahiro Sasaki, Keitaro Takahashi, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Sayaka Yuzawa, Kentaro Moriichi, Yusuke Mizukami, Mikihiro Fujiya and Toshikatsu Okumura |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hiroki Tanabe, MD, PhD, Assistant Professor, Division of Metabolism and Biosystemic Science, Gastroenterology and Hematology/Oncology Department of Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa 078-8510, Hokkaido, Japan. tant@asahikawa-med.ac.jp |
| Key Words |
Rectal cancer; Mucinous adenocarcinoma; Endoscopic submucosal dissectio; TP53; Colitic cancer pathway; Case report |
| Core Tip |
Colorectal mucinous adenocarcinoma, as characterized by an abundant mucinous component, is a rare histological subtype frequently diagnosed at an advanced stage. Intramucosal mucinous adenocarcinoma was dissected by endoscopic submucosal dissection and local recurrence was detected three years after the treatment. Genetic analysis showed pathogenic alterations of RNF43, TP53, and SMAD4. This case of mucinous mucosal adenocarcinoma was suggested to have an aggressive phenotype based on the treatment course and advanced genotype identified by target sequencing. Careful and close follow-up should be performed, and additional surgery should be considered when managing patients with mucinous adenocarcinoma. |
| Publish Date |
2023-01-10 08:49 |
| Citation |
Murakami Y, Tanabe H, Ono Y, Sugiyama Y, Kobayashi Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Yuzawa S, Moriichi K, Mizukami Y, Fujiya M, Okumura T. Local recurrence after successful endoscopic submucosal dissection for rectal mucinous mucosal adenocarcinoma: A case report. World J Gastrointest Oncol 2023; 15(1): 186-194 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i1/186.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i1.186 |
