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9/5/2014 1:53:00 PM | Browse: 876 | Download: 706
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 8147
Country/Territory Germany
Received
2013-12-18 11:01
Peer-Review Started
2013-12-19 09:21
To Make the First Decision
2014-01-08 14:54
Return for Revision
2014-01-21 15:01
Revised
2014-01-24 19:39
Second Decision
2014-03-17 14:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-17 14:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-21 17:59
Typeset the Manuscript
2014-05-19 07:54
Publish the Manuscript Online
2014-05-20 17:09
ISSN 2150-5330 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Minireviews
Article Title Role of gamma-delta T cells in liver inflammation and fibrosis
Manuscript Source Invited Manuscript
All Author List Linda Hammerich and Frank Tacke
Funding Agency and Grant Number
Funding Agency Grant Number
German Research Foundation DFG Ta434/2-1
German Research Foundation SFB/TRR57
Interdisciplinary Center for Clinical Research (IZKF) Aachen
Corresponding Author Frank Tacke, MD, PhD, Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany. frank.tacke@gmx.net
Key Words Liver fibrosis; Liver cirrhosis; Interleukin-17; Gamma/delta T cells; Cytokines
Core Tip The liver is particularly enriched in unconventional T cells expressing the gamma-delta T cell receptor and the functional role of these gamma-delta (??) T cells in liver diseases is being intensively investigated at present. ?? T cells accumulate in inflamed liver and their function appears highly dependent on the distinct subsets. In principle, ???T cells can be protective as well as pathogenic in the context of liver inflammation. This review summarizes the current knowledge of ?? T cell effector functions and the cytokines produced by these cells in human liver diseases and murine experimental models of acute and chronic liver injury.
Publish Date 2014-05-20 17:09
Citation Hammerich L, Tacke F. Role of gamma-delta T cells in liver inflammation and fibrosis. World J Gastrointest Pathophysiol 2014; 5(2): 107-113
URL http://www.wjgnet.com/2150-5330/full/v5/i2/107.htm
DOI http://dx.doi.org/10.4291/wjgp.v5.i2.107
Full Article (PDF) WJGP-5-107.pdf
Full Article (Word) WJGP-5-107.doc
Manuscript File 8147-Review.docx
Answering Reviewers 8147-Answering reviewers.pdf
Copyright License Agreement 8147-Copyright assignment.pdf
Peer-review Report 8147-Peer reviewer(s).pdf
Scientific Editor Work List 8147-Scientific editor work list.doc