| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Intraprocedural gastric juice analysis as compared to rapid urease test for real-time detection of Helicobacter pylori
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Riccardo Vasapolli, Florent Ailloud, Sebastian Suerbaum, Jens Neumann, Nadine Koch, Lukas Macke, Jörg Schirra, Julia Mayerle, Peter Malfertheiner and Christian Schulz |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Deutsches Zentrum für Infektionsforschung, Partner Site Munich, Germany |
TTU 06.715_00 |
| Bavarian Ministry of Science and the Arts within the framework of the Bavarian Research Network “New Strategies Against Multi-Resistant Pathogens by Means of Digital Networking – bayresq.net” |
|
|
| Corresponding Author |
Christian Schulz, MD, Deputy Director, Medical Department ІІ, University Hospital LMU Munich, Marchionini Strasse 15, Munich 81377, Germany. chr.schulz@med.uni-muenchen.de |
| Key Words |
Helicobacter pylori diagnostic; Chronic gastritis; Gastric juice; Endofaster; Rapid urease test; Antimicrobial susceptibility testing |
| Core Tip |
Diagnosis of Helicobacter pylori (H. pylori) infection can be rapidly achieved within the framework of gastroscopy by rapid urease test (RUT) or by gastric juice analysis with Endofaster. In this prospective observational study, we compared the accuracy of these two methods. Gastric juice analysis with Endofaster could reliably detect H. pylori with high accuracy, showing a diagnostic performance comparable to that of RUT and a major advantage of an immediate result. Intraprocedural H. pylori detection (or exclusion) is crucial to optimize the diagnostic approach and improve the management of infection. The diagnosis of Endofaster may guide additional sampling for antibiotic susceptibility testing in positive patients or avoid unnecessary biopsies in negative patients. |
| Publish Date |
2023-03-10 07:29 |
| Citation |
Vasapolli R, Ailloud F, Suerbaum S, Neumann J, Koch N, Macke L, Schirra J, Mayerle J, Malfertheiner P, Schulz C. Intraprocedural gastric juice analysis as compared to rapid urease test for real-time detection of Helicobacter pylori. World J Gastroenterol 2023; 29(10): 1638-1647 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i10/1638.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i10.1638 |
