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10/24/2014 5:02:00 PM | Browse: 957 | Download: 866
Publication Name World Journal of Transplantation
Manuscript ID 8249
Country United States
Received
2013-12-22 14:15
Peer-Review Started
2013-12-22 19:48
To Make the First Decision
2014-02-13 16:26
Return for Revision
2014-02-20 22:33
Revised
2014-03-16 17:53
Second Decision
2014-06-27 17:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-27 17:50
Articles in Press
2014-06-27 18:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-10-22 17:08
Publish the Manuscript Online
2014-10-24 17:01
ISSN 2220-3230 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Autobiography
Article Title Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study
Manuscript Source Invited Manuscript
All Author List Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study
Funding Agency and Grant Number
Funding Agency Grant Number
National Taiwan University
Corresponding Author Dr. Ching-Shwun Lin, Department of Urology, School of Medicine, University of California, 533 Parnassus Ave, San Francisco, CA 94143-0738, United States. clin@urology.ucsf.edu
Key Words Canine osteoarthritis; Adipose-derived stem cells; Intra-articular transplantation; Intra-articular injection; Veterinary clinical study
Core Tip Intra-articular injection of autologous adipose-derived stem cells (ADSCs) has been shown to be effective in treating osteoarthritis in dogs. However, most veterinary clinics lack the equipment and expertise for ADSC isolation. The present study showed that intra-articular injection of porcine ADSCs into the diseased stifle joint of three dogs improved their mobility and activity and lessened their pain. The injection of porcine ADSCs elicited no signs of inflammation or immunological reaction. Thus, porcine ADSCs can substitute for autologous canine ADSCs, and such a treatment strategy can drastically reduce treatment cost.
Publish Date 2014-10-24 17:01
Citation Tsai SY, Huang YC, Chueh LL, Yeh LS, Lin CS. Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study. World J Transplant 2014; 4(3): 196-205
URL http://www.wjgnet.com/2220-3230/full/v4/i3/196.htm
DOI http://dx.doi.org/10.5500/wjt.v4.i3.196
Full Article (PDF) WJT-4-196.pdf
Full Article (Word) WJT-4-196.doc
Manuscript File 8249-Review.docx
Answering Reviewers 8249-Answering reviewers.pdf
Copyright License Agreement 8249-Copyright assignment.pdf
Peer-review Report 8249-Peer review(s).pdf
Scientific Misconduct Check 8249-CrossCheck.jpg
Scientific Editor Work List 8249-Scientific editor work list.pdf