Publication Name	World Journal of Clinical Oncology
Manuscript ID	8297
Country	United Kingdom

Received	2013-12-24 11:53
Peer-Review Started	2013-12-25 12:28
To Make the First Decision	2014-01-08 13:57
Return for Revision	2014-01-17 10:55
Revised	2014-01-26 02:28
Second Decision	2014-05-19 09:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-19 09:18
Articles in Press	2014-05-23 09:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-24 14:18
Publish the Manuscript Online	2014-08-01 16:16

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Phytoestrogens and prevention of breast cancer: The contentious debate
Manuscript Source	Invited Manuscript
All Author List	Iqra Bilal, Avidyuti Chowdhury, Juliet Davidson and Saffron Whitehead
Funding Agency and Grant Number
Corresponding Author	Saffron Whitehead, Professor, Department of Basic Medical Sciences, St George’s University of London, Cranmer Terrace, London SW17 0RE, United Kingdom. saffron@sgul.ac.uk
Key Words	Phytoestrogens; Breast cancer; Cell signalling; Cell cycle; Epigenomics
Core Tip	Phytoestrogens have multiple actions within target cells, including the epigenome, which could be beneficial to the development and progression of breast cancer. In this brief review the action of phytoestrogens on oestrogen receptors, cell signalling pathways, regulation of the cell cycle, apoptosis, steroid synthesis and epigenetic events in relation to breast cancer are discussed. The difficulties in interpreting experimental evidence relating to the beneficial effects of phytoestrogens in light of dietary/supplementary intake and bioavailability of ingested phytoestrogens is also addressed.
Publish Date	2014-08-01 16:16
Citation	Bilal I, Chowdhury A, Davidson J, Whitehead S. Phytoestrogens and prevention of breast cancer: The contentious debate. World J Clin Oncol 2014; 5(4): 705-712
URL	http://www.wjgnet.com/2218-4333/full/v5/i4/705.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i4.705

Full Article (PDF)	WJCO-5-705.pdf
Full Article (Word)	WJCO-5-705.doc
Manuscript File	8297-Review.doc
Answering Reviewers	8297-Answering reviewers.pdf
Copyright License Agreement	8297-Copyright assignment.pdf
Peer-review Report	8297-Peer review(s).pdf
Scientific Editor Work List	8297-Scientific editor work list.pdf