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Articles Published Processes
5/26/2023 11:17:59 AM | Browse: 267 | Download: 549
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Received |
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2023-01-12 06:02 |
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Peer-Review Started |
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2023-01-12 06:04 |
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To Make the First Decision |
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Return for Revision |
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2023-01-31 17:46 |
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Revised |
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2023-02-17 01:44 |
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Second Decision |
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2023-03-21 03:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-03-21 07:37 |
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Articles in Press |
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2023-03-21 07:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-04-24 06:33 |
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Publish the Manuscript Online |
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2023-05-26 11:17 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Review |
| Article Title |
Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Li-Yi Huang, Xin Sun, Hong-Xia Pan, Lu Wang, Cheng-Qi He and Quan Wei |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key R&D Program of China |
2020YFC2008502 |
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| Corresponding Author |
Quan Wei, MD, PhD, Professor, Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital/West China School of Medicine, Sichuan University, No. 37 Guoxue Lane, Chengdu 610044, Sichuan Province, China. weiquan@scu.edu.cn |
| Key Words |
Spinal cord injury; Bone marrow derived mesenchymal stem cells; Neuroprotection; Axon; Myelin; Inhibitory microenvironment |
| Core Tip |
In this work, we review the specific mechanism of bone marrow-derived mesenchymal stem cell (BMMSC) in spinal cord injury (SCI) repair mainly from the following aspects: Neuroprotection, neuronal circuit, axon sprouting and or regeneration, myelin regeneration, inhibitory microenvironment, glial scar formation, immunomodulation, and angiogenesis. Additionally, we also summarize the latest evidence on application of BMMSC in clinical trials and further discuss the challenges and future directions for stem cell therapy in SCI models. |
| Publish Date |
2023-05-26 11:17 |
| Citation |
Huang LY, Sun X, Pan HX, Wang L, He CQ, Wei Q. Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges. World J Stem Cells 2023; 15(5): 385-399 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i5/385.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i5.385 |
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