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Articles Published Processes
5/12/2023 9:13:35 AM | Browse: 239 | Download: 798
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Received |
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2023-01-13 08:30 |
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Peer-Review Started |
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2023-01-13 08:32 |
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To Make the First Decision |
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Return for Revision |
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2023-01-22 04:26 |
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Revised |
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2023-02-01 14:43 |
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Second Decision |
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2023-04-07 01:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-07 07:10 |
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Articles in Press |
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2023-04-07 07:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-06 15:30 |
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Publish the Manuscript Online |
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2023-05-12 09:13 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Acute respiratory distress syndrome and severe pneumonitis after atezolizumab plus bevacizumab for hepatocellular carcinoma treatment: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Su Hyeon Cho, Ga Ram You, Chan Park, Sang-Geon Cho, Jong Eun Lee, Sung Kyu Choi, Sung Bum Cho and Jae Hyun Yoon |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chonnam National University Hospital Biomedical Research Institute |
BCRE22158 |
| Chonnam National University Hospital Biomedical Research Institute |
NRF-2021R1F1A1061719 |
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| Corresponding Author |
Jae Hyun Yoon, MD, Associate Professor, Department of Gastroenterology and Hepatology, Chonnam National University Hospital and Medical School, Je-bong ro 42, Dong Gu, Gwangju 61469, South Korea. zenmake14@gmail.com |
| Key Words |
Hepatocellular carcinoma; Systemic therapy; Adverse events; Pneumonitis; Atezolizumab; Acute respiratory distress syndrome |
| Core Tip |
Nowadays, the combination therapy of atezolizumab and bevacizumab is recommended as the first-line systemic treatment for advanced hepatocellular carcinomas. A global phase III study and recent real-world studies demonstrated rare life-threatening adverse events of atezolizumab and bevacizumab. However, our patient underwent acute respiratory distress syndrome and finally died three days after treatment. To the best of our knowledge, this is the first case of severe respiratory failure resulting in death with a very short interval from atezolizumab and bevacizumab administration. Therefore, we suggest close monitoring of lung toxicity after therapy. |
| Publish Date |
2023-05-12 09:13 |
| Citation |
Cho SH, You GR, Park C, Cho SG, Lee JE, Choi SK, Cho SB, Yoon JH. Acute respiratory distress syndrome and severe pneumonitis after atezolizumab plus bevacizumab for hepatocellular carcinoma treatment: A case report. World J Gastrointest Oncol 2023; 15(5): 892-901 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i5/892.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i5.892 |
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