Publication Name	World Journal of Medical Genetics
Manuscript ID	8397
Country	India

Received	2013-12-28 11:39
Peer-Review Started	2013-12-28 15:22
To Make the First Decision	2014-03-12 17:04
Return for Revision	2014-03-21 19:14
Revised	2014-04-10 15:00
Second Decision	2014-05-14 16:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-14 16:39
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-27 18:57
Publish the Manuscript Online	2014-05-28 15:12

ISSN	2220-3184 (online)
Open Access
Copyright
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Category	Infectious Diseases
Manuscript Type	Review
Article Title	Acquisition and dissemination mechanisms of CTXΦ in Vibrio cholerae: New paradigm for dif residents
Manuscript Source	Invited Manuscript
All Author List	Bhabatosh Das, G Balakrish Nair and Rupak K Bhadra
Funding Agency and Grant Number	Funding Agency Grant Number Department of Science Technology SB/FT/LS-309/2012 Government of India (GOI) and the Department of Biotechnology BT/MB/THSTI/HMC-SFC/2011 Council of Scientific and Industrial Research, GOI and Indian Council of Medical Research, GOI
Corresponding Author	Rupak K Bhadra, MSc, PhD, FAScT, Senior Principal Scientist, Infectious Diseases and Immunology Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India. rupakbhadra@iicb.res.in
Key Words	Vibrio cholerae; Cholera toxin phage; VGJΦ; Plasmids; Integrative mobile genetic element; XerC; XerD; Dimer resolution sites; attP; attB
Core Tip	Integrative mobile genetic element (IMGE) like prophage, plasmid, transposon or genomic island plays crucial roles in the evolution of bacterial pathogens. The Vibrio cholerae (V. cholerae) genome harbors several such IMGEs, which provides virulence, antibiotic resistance and other fitness traits to cholera pathogen and directly contributes in its evolution. Cholera toxin encoding phage (CTXΦ) is a well characterized IMGE, found integrated in the dimer resolution sites of all epidemic V. cholerae strains and exploits host encoded XerC and XerD recombinases for its lysogenic conversion. In this review we discussed about integration and dissemination of CTXΦ and related IMGEs of V. cholerae.
Publish Date	2014-05-28 15:12
Citation	Das B, Nair GB, Bhadra RK. Acquisition and dissemination mechanisms of CTXΦ in Vibrio cholerae: New paradigm for dif residents. World J Med Genet 2014; 4(2): 27-33
URL	http://www.wjgnet.com/2220-3184/full/v4/i2/27.htm
DOI	http://dx.doi.org/10.5496/wjmg.v4.i2.27

Full Article (PDF)	WJMG-4-27.pdf
Full Article (Word)	WJMG-4-27.doc
Manuscript File	8397-Review.doc
Answering Reviewers	8397-Answering reviewers.pdf
Copyright License Agreement	8397-Copyright assignment.pdf
Peer-review Report	8397-Peer review(s).pdf
Scientific Editor Work List	8397-Scientific editor work list.pdf