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8/22/2014 7:36:00 PM | Browse: 1179 | Download: 782
Publication Name World Journal of Diabetes
Manuscript ID 8414
Country/Territory Japan
Received
2013-12-28 12:54
Peer-Review Started
2013-12-28 16:48
To Make the First Decision
2014-02-13 16:23
Return for Revision
2014-02-20 23:02
Revised
2014-03-01 01:23
Second Decision
2014-06-03 16:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-03 16:34
Articles in Press
2014-06-03 16:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-05 18:41
Publish the Manuscript Online
2014-08-17 13:16
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Hepatocyte growth factor, a biomarker of macroangiopathy in diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Hiroyuki Konya, Masayuki Miuchi, Kahori Satani, Satoshi Matsutani, Taku Tsunoda, Yuzo Yano, Tomoyuki Katsuno, Tomoya Hamaguchi, Jun-Ichiro Miyagawa and Mitsuyoshi Namba
Funding Agency and Grant Number
Corresponding Author Hiroyuki Konya, MD, PhD, Department of Internal Medicine, Ashiya Municipal Hospital, 39-1, Asahigaoka-cho, Ashiya, Hyogo 659-8502, Japan. h-dyer@mvi.biglobe.ne.jp
Key Words Hepatocyte growth factor; Diabetes mellitus; Carotid atherosclerosis; Macroangiopathy; Biomarker
Core Tip Hepatocyte growth factor (HGF) has been a mesenchymal-derived polyphenic factor which modulates development, motion, and morphosis of diverse cells, and has been regarded as a humor intermediator of epithelial-mesenchymal interplays. The serum levels of HGF in diabetes mellitus (DM) subjects might be assayed by balancing of stimulators (hypertension, atheromatous arteriosclerosis, etc.) and suppressors (hyperglycemia, transforming growth factor-, angiotensin II, etc.). The elevated serum level of HGF might have been regarded as an indicator of the DM involvements seriousness. Accordingly, the concentration of serum HGF might be a new and meaningful biomarker of macroangiopathy in DM subjects.
Publish Date 2014-08-17 13:16
Citation Konya H, Miuchi M, Satani K, Matsutani S, Tsunoda T, Yano Y, Katsuno T, Hamaguchi T, Miyagawa JI, Namba M. Hepatocyte growth factor, a biomarker of macroangiopathy in diabetes mellitus. World J Diabetes 2014; 5(5): 678-688
URL http://www.wjgnet.com/1948-9358/full/v5/i5/678.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i5.678
Full Article (PDF) WJD-5-678.pdf
Full Article (Word) WJD-5-678.doc
Manuscript File 8414-Review.docx
Answering Reviewers 8414-Answering reviewers.pdf
Copyright License Agreement 8414-Copyright assignment.pdf
Peer-review Report 8414-Peer review(s).pdf
Scientific Misconduct Check 8414-CrossCheck.jpg
Scientific Editor Work List 8414-Scientific editor work list.pdf