ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Retrospective Study |
Article Title |
Hemoglobin, albumin, lymphocyte, and platelet score as a predictor of prognosis in metastatic gastric cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yakup Duzkopru, Abdulkadir Kocanoglu, Ozlem Dogan, Hayriye Sahinli, Ebru Cilbir and Mustafa Altinbas |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Yakup Duzkopru, MD, Academic Fellow, Doctor, Doctor, Department of Medical Oncology, Ankara Etlik City Hospital, Varlik Neighbourhood, Halil Sezai Erkut Street, Yenimahalle, Ankara 06170, Türkiye. yakupduzkopru@gmail.com |
Key Words |
Biomarker; Hemoglobin, albumin, lymphocyte, and platelet score; Gastric cancer; Nutritional index; Prognosis; Survival |
Core Tip |
Median overall survival (OS) was 10.4 mo in the high hemoglobin, albumin, lymphocyte, and platelet (HALP) group and 7.5 mo in the low HALP group. There was a statistically significant difference between the groups in terms of age (P < 0.001), second-line chemotherapy (P < 0.001), sex (P = 0.035), and HALP score (P = 0.004). The HALP score has been demonstrated to be useful as a prognostic factor in a variety of cancer types, including genitourinary and gastrointestinal malignancies. Our study is the first to investigate the HALP score in patients with metastatic gastric cancer. We found that patients with high HALP scores had longer OS. Given its simplicity and low cost, we think the HALP score can be utilized to manage patients with gastric cancer. |
Publish Date |
2023-09-13 09:17 |
Citation |
Duzkopru Y, Kocanoglu A, Dogan O, Sahinli H, Cilbir E, Altinbas M. Hemoglobin, albumin, lymphocyte, and platelet score as a predictor of prognosis in metastatic gastric cancer. World J Gastrointest Oncol 2023; 15(9): 1626-1635 |
URL |
https://www.wjgnet.com/1948-5204/full/v15/i9/1626.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v15.i9.1626 |