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8/26/2014 9:28:00 AM | Browse: 383 | Download: 436
Publication Name World Journal of Orthopedics
Manuscript ID 8566
Country of Manuscript Source Italy
Received
2013-12-30 12:25
Peer-Review Started
2013-12-30 15:43
To Make the First Decision
2014-02-13 16:20
Return for Revision
2014-02-20 23:59
Revised
2014-03-04 07:50
Second Decision
2014-04-19 14:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-19 14:37
Articles in Press
2014-05-23 12:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-07-01 09:01
Publish the Manuscript Online
2014-07-19 23:48
ISSN 2218-5836 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript Type Topic Highlights
Article Title Osteoporosis and obesity: Role of Wnt pathway in human and murine models
Manuscript Source Invited Manuscript
All Author List Graziana Colaianni, Giacomina Brunetti, Maria Felicia Faienza, Silvia Colucci and Maria Grano
Funding Agency and Grant Number
Corresponding author Graziana Colaianni, PhD, Department of Basic Medical Science, Neuroscience and Sense Organs, Section of Human Anatomy and Histology, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy. graziana.colaianni@libero.it
Keywords Osteoporosis; Obesity; Bone; Fat; Wnt; Peroxisome proliferators activated receptor-γ; Dickkopf; Sclerostin
Core Tip Here we will discuss the role of the key molecules influencing adipocytes and osteoblasts differentiation, which are peroxisome proliferators activated receptor-? and Wnts, respectively. Besides these proteins, the Wnt inhibitor molecules are also necessary to control the Wnt signalling balance from active to inactive state, in favour of osteogenesis or adipogenesis. It seems remarkably important a deepen analysis of these molecules, not only for their involvement in the regulation of the differentiation processes but also in coordinating the switch toward osteo- or adipo-genesis fate within bone marrow.
Publish Date 2014-07-19 23:48
Citation Colaianni G, Brunetti G, Faienza MF, Colucci S, Grano M. Osteoporosis and obesity: Role of Wnt pathway in human and murine models. World J Orthop 2014; 5(3): 242-246
Url http://www.wjgnet.com/2218-5836/full/v5/i3/242.htm
DOI http://dx.doi.org/10.5312/wjo.v5.i3.242
Full Article (PDF) WJO-5-242.pdf
Full Article (Word) WJO-5-242.doc
Manuscript File 8566-Review.doc
Answering Reviewers 8566-Answering reviewers.pdf
Copyright License Agreement 8566-Copyright assignment.pdf
Peer-review Report 8566-Peer review(s).pdf
Scientific Editor Work List 8566-Scientific editor work list.doc