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9/18/2014 7:49:00 PM | Browse: 1261 | Download: 1278
Publication Name World Journal of Gastroenterology
Manuscript ID 8569
Country/Territory Chile
Received
2013-12-31 08:21
Peer-Review Started
2013-12-31 09:12
To Make the First Decision
2014-01-14 17:40
Return for Revision
2014-01-20 09:34
Revised
2014-03-27 04:43
Second Decision
2014-04-29 12:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-29 14:17
Articles in Press
2014-05-23 10:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-21 19:12
Publish the Manuscript Online
2014-09-18 19:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Evidence-Based Medicine
Article Title Management of nonalcoholic fatty liver disease: An evidence-based clinical practice review
Manuscript Source Unsolicited Manuscript
All Author List Juan P Arab, Roberto Candia, Rodrigo Zapata, Cristián Muñoz, Juan P Arancibia, Jaime Poniachik, Alejandro Soza, Francisco Fuster, Javier Brahm, Edgar Sanhueza, Jorge Contreras, M Carolina Cuellar, Marco Arrese and Arnoldo Riquelme
Funding Agency and Grant Number
Funding Agency Grant Number
Chilean Society of Gastroenterology (in part)
Fondo Nacional De Ciencia y Tecnología de Chile 1110455 (to Arrese M)
Fondo Nacional De Ciencia y Tecnología de Chile 1120652 (to Riquelme A)
Comisión Nacional de Investigación, Ciencia y Tecnología, CONICYT
Corresponding Author Arnoldo Riquelme, MD, MMedEd, Departamento de Gastroenterología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 367, 8330024 Santiago, Chile. a.riquelme.perez@gmail.com
Key Words Nonalcoholic fatty liver disease; Steatosis; Consensus; Evidence-based medicine; Treatment
Core Tip Current nonalcoholic fatty liver disease (NAFLD) management is rapidly evolving, and new pathophysiology-based therapies are expected to be introduced in the near future. All NAFLD patients should be evaluated using a three-focused approach that considers risks of liver disease, diabetes and cardiovascular events. The final recommendations of this consensus support the indication of lifestyle changes, including diet and exercise, for all patients with NAFLD. Proven pharmacological therapies only consider vitamin E and pioglitazone, which can be used in nondiabetic patients with biopsy-proven nonalcoholic steatohepatitis (the progressive form of NAFLD), although the long-term safety and efficacy of these therapies have not been established.
Publish Date 2014-09-18 19:50
Citation Arab JP, Candia R, Zapata R, Muñoz C, Arancibia JP, Poniachik J, Soza A, Fuster F, Brahm J, Sanhueza E, Contreras J, Cuellar MC, Arrese M, Riquelme A. Management of nonalcoholic fatty liver disease: An evidence-based clinical practice review. World J Gastroenterol 2014; 20(34): 12182-12201
URL http://www.wjgnet.com/1007-9327/full/v20/i34/12182.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i34.12182
Full Article (PDF) WJG-20-12182.pdf
Full Article (Word) WJG-20-12182.doc
Manuscript File 8569-Review.doc
Answering Reviewers 8569-Answering reviewers.pdf
Copyright License Agreement 8569-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 8569-Language certificate.pdf
Peer-review Report 8569-Peer reviews.pdf
Scientific Editor Work List 8569-Scientific editor work list.pdf