Publication Name	World Journal of Gastroenterology
Manuscript ID	8723
Country	China

Received	2014-01-04 12:37
Peer-Review Started	2014-01-04 16:02
To Make the First Decision	2014-01-24 13:41
Return for Revision	2014-01-24 21:42
Revised	2014-02-07 19:44
Second Decision	2014-03-05 14:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-05 14:50
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-17 17:47
Typeset the Manuscript	2014-04-22 09:00
Publish the Manuscript Online	2014-04-29 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Lin Li, De-Zhao Lu, You-Ming Li, Xue-Qun Zhang, Xin-Xin Zhou and Xi Jin
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81000169 National Natural Science Foundation of China 81100277 National Natural Science Foundation of China 81370008 National Natural Science Foundation of China 81200284 Excellent Young Investigator Foundation of the Health Bureau of Zhejiang Province 2010QNA011 Excellent Young Investigator Natural Science Foundation of Zhejiang Province R2110159 Project of Zhejiang Traditional Chinese Medicine Administration Bureau 2010ZA065 Fundamental Research Funds for the Central Universities 2013QNA702
Corresponding Author	Dr. Xi Jin, the First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@hotmail.com
Key Words	Nonalcoholic steatohepatitis; Hadha; Proteomics; Rat model
Core Tip	Nonalcoholic fatty liver disease (NAFLD) is a major worldwide cause of chronic liver diseases, and nonalcoholic steatohepatitis (NASH) plays a critical role as a “turning point” in the development of NAFLD. Nevertheless, the pathogenesis of NASH remains unclear, and mitochondrial dysfunction is known to be actively involved. To date, no study has reported on specific protein expression patterns in NASH mitochondria. We have, for the first time, performed a proteomic analysis of mitochondria from NASH rats, aiming to provide a protein reservoir for in-depth analyses of NASH mechanisms and for the exploration of potential therapeutics.
Publish Date	2014-04-29 09:53
Citation	Li L, Lu DZ, Li YM, Zhang XQ, Zhou XX, Jin X. Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. World J Gastroenterol 2014; 20(16): 4778-4786
URL	http://www.wjgnet.com/1007-9327/full/v20/i16/4778.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i16.4778

Full Article (PDF)	WJG-20-4778.pdf
Full Article (Word)	WJG-20-4778.doc
Manuscript File	8723-Review.doc
Answering Reviewers	8723-Answering reviewers.pdf
Copyright License Agreement	8723-Copyright assingment.pdf
Non-Native Speakers of English Editing Certificate	8723-Language certificate.pdf
Peer-review Report	8723-Peer review(s).pdf
Scientific Editor Work List	8723-Scientific editor work list.doc