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2/7/2024 2:35:41 AM | Browse: 86 | Download: 63
Publication Name World Journal of Orthopedics
Manuscript ID 88347
Country/Territory China
Received
2023-09-21 05:40
Peer-Review Started
2023-09-21 05:42
To Make the First Decision
Return for Revision
2023-11-29 06:57
Revised
2023-12-01 08:06
Second Decision
2024-01-11 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-01-11 07:06
Articles in Press
2024-01-11 07:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
2024-01-10 02:15
Typeset the Manuscript
2024-01-23 00:21
Publish the Manuscript Online
2024-02-07 02:35
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Editorial
Article Title Mitochondrial dysfunction in type 2 diabetes: A neglected path to skeletal muscle atrophy
Manuscript Source Invited Manuscript
All Author List Jian-Jun Wu, Hui-Min Xian, Da-Wei Yang and Fan Yang
ORCID
Author(s) ORCID Number
Da-Wei Yang http://orcid.org/0000-0002-7217-9383
Fan Yang http://orcid.org/0000-0003-4676-3778
Funding Agency and Grant Number
Funding Agency Grant Number
the Foundation of State Key Laboratory of Component-based Chinese Medicine CBCM2023107
National Natural Science Foundation of China 81901853
Specially Funded Scientific Research Project of the Fourth Affiliated Hospital of Harbin Medical University HYDSYTB202126
Corresponding Author Fan Yang, MD, MMed, PhD, Associate Research Scientist, Occupational Physician, Postdoc, Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, No. 246 Xuefu Road, Nangang District, Harbin 150001, Heilongjiang Province, China. yangfana@sina.com
Key Words Mfn-2; Oxidative stress; Mitochondria metabolism; Skeletal muscle atrophy; Diabetes
Core Tip Type 2 diabetes mellitus (T2DM) poses a substantial global health challenge. Attaining optimal glycemic control is crucial for mitigating complications and mortality associated with T2DM. However, recent research has unveiled a frequently overlooked complication: The progressive atrophy of skeletal muscle. Mitochondria, pivotal for cellular energy production, uphold a delicate equilibrium in their fusion and fission processes. Investigating the interplay between mitochondrial dysfunction and skeletal muscle atrophy in T2DM is imperative for advancing our comprehension of diabetes. Findings from cellular and animal models suggest that targeting mitochondrial dynamics, particularly through the modulation of Mfn-2, holds promise as a therapeutic strategy to counteract muscle atrophy induced by diabetes. This approach underscores a novel intersection in the management of diabetic complications, forging a connection between metabolic control and muscular health.
Publish Date 2024-02-07 02:35
Citation Wu JJ, Xian HM, Yang DW, Yang F. Mitochondrial dysfunction in type 2 diabetes: A neglected path to skeletal muscle atrophy. World J Orthop 2024; 15(2): 101-104
URL https://www.wjgnet.com/2218-5836/full/v15/i2/101.htm
DOI https://dx.doi.org/10.5312/wjo.v15.i2.101
Full Article (PDF) WJO-15-101-with-cover.pdf
Full Article (Word) WJO-15-101.docx
Manuscript File 88347_Auto_Edited-CL-WangTQ-YJP.docx
Answering Reviewers 88347-Answering reviewers.pdf
Audio Core Tip 88347-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 88347-Conflict-of-interest statement.pdf
Copyright License Agreement 88347-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 88347-Grant application form(s).PDF
Non-Native Speakers of English Editing Certificate 88347-Language certificate.pdf
Peer-review Report 88347-Peer-review(s).pdf
Scientific Misconduct Check 88347-Bing-Lin C-2.png
Scientific Editor Work List 88347-Scientific editor work list.pdf