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8/25/2014 3:23:00 PM | Browse: 410 | Download: 412
Publication Name World Journal of Radiology
Manuscript ID 9160
Country/Territory Italy
Received
2014-01-24 15:29
Peer-Review Started
2014-01-24 22:53
To Make the First Decision
2014-03-12 16:45
Return for Revision
2014-03-20 20:32
Revised
2014-04-13 00:05
Second Decision
2014-05-19 09:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-19 09:28
Articles in Press
2014-05-23 12:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-06-17 19:12
Publish the Manuscript Online
2014-06-28 15:27
ISSN 1949-8470 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Frontier
Article Title White matter abnormalities: Insights into the pathophysiology of major affective disorders
Manuscript Source Unsolicited Manuscript
All Author List Gianluca Serafini, Xenia Gonda, Zoltan Rihmer, Paolo Girardi and Mario Amore
Funding Agency and Grant Number
Corresponding author Gianluca Serafini, MD, PhD, Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza University of Rome, 1035-1039, Via di Grottarossa, 00189 Rome, Italy. gianluca.serafini@uniroma1.it
Key Words White matter hyperintensities; Major affective disorders; Suicidal behaviour; Neuroimaging; Outcome
Core Tip Understanding neural correlates underlying psychiatric morbidity over time is critical but, to date, structural magnetic resonance imaging studies identified only not stable risk predictors of unfavourable outcome in psychiatric populations. The presence of white matter hyperintensities (WMHs) has been commonly associated with a poor outcome in individuals with major affective disorders. Based on our studies, subjects with WMHs may be considered at higher suicidal risk than those without and the severity of WMHs as assessed by the Fazekas modified scale may serve as a trait marker of disease. WMHs may represent an interesting neurobiological marker between the underlying vulnerability and clinical presentation of major affective disorders.
Publish Date 2014-06-28 15:27
Citation Serafini G, Gonda X, Rihmer Z, Girardi P, Amore M. White matter abnormalities: Insights into the pathophysiology of major affective disorders. World J Radiol 2014; 6(6): 223-229
Url http://www.wjgnet.com/1949-8470/full/v6/i6/223.htm
DOI http://dx.doi.org/10.4329/wjr.v6.i6.223
Full Article (PDF) WJR-6-223.pdf
Full Article (Word) WJR-6-223.doc
Manuscript File 9160-Review.doc
Answering Reviewers 9160-Answering reviewers.pdf
Copyright License Agreement 9160-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 9160-Language certificate.pdf
Peer-review Report 9160-Peer review(s).pdf
Scientific Editor Work List 9160-Scientific editor work list.pdf