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10/20/2014 9:54:00 AM | Browse: 305 | Download: 257
Publication Name World Journal of Ophthalmology
Manuscript ID 9484
Country of Manuscript Source Germany
Received
2014-02-13 17:32
Peer-Review Started
2014-02-17 13:59
To Make the First Decision
2014-03-12 16:37
Return for Revision
2014-03-17 16:56
Revised
2014-03-19 15:33
Second Decision
2014-06-11 13:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-11 13:41
Articles in Press
2014-06-11 13:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-09-28 17:45
Publish the Manuscript Online
2014-10-20 09:43
ISSN 2218-6239 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Ophthalmology
Manuscript type Minireviews
Article Title Blue light induced retinal oxidative stress: Implications for macular degeneration
Manuscript Source Invited Manuscript
All Author List Richard HW Funk, Ulrike Schumann, Katrin Engelmann, Klio A Becker and Cora Roehlecke
Funding Agency and Grant Number
Correspondence To Richard HW Funk, Prof. Dr., Institute of Anatomy, TU - Dresden, Fiedlerstrasse 42, Dresden, 01307, Germany richard-funk@tu-dresden.de
Keywords blue light; oxidative stress; retina; photoreceptor; age related macular degeneration
Core Tip The mechanisms that can lead to damage and subsequently to degenerative diseases like age related macular degeneration (AMD) remain unclear, especially whether light induced radical stress or damage is a direct interaction of light with photoreceptors or a secondary mechanism. Recently it was shown that after blue light not only the mitochondria in the retinal cells can produce massive amounts of of reactive oxygen species (ROS) but also the outer segments of photoreceptors. Furthermore, there are indications that the outer segments harbour ectopic enzymes of the respiratory chain being an additional source of ROS production. In the light of these novel aspects we have compiled a review revisting the data of oxidative stress in the retina - possibly one cause for development of AMD.
Publish Date 2014-10-20 09:43
Citation Funk RHW, Schumann U, Engelmann K, Becker KA, Roehlecke C. Blue light induced retinal oxidative stress: Implications for macular degeneration. World J Ophthalmol 2014; 4(3): 29-34
Url http://www.wjgnet.com/2218-6239/full/v4/i3/29.htm
DOI http://dx.doi.org/10.5318/wjo.v4.i3.29
Full Article (PDF) WJO-4-29.pdf
Full Article (Word) WJO-4-29.doc
Manuscript File 9484-Review.docx
Answering Reviewers 9484-Answering reviewers.pdf
Copyright License Agreement 9484-Copyright assignment.pdf
Peer-review Report 9484-Peer review(s).pdf
Scientific Misconduct Check 9484-CrossCheck.jpg
Scientific Editor Work List 9484-Scientific editor work list.pdf