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12/5/2014 11:43:00 AM | Browse: 823 | Download: 951
Publication Name World Journal of Gastroenterology
Manuscript ID 9908
Country/Territory Norway
Received
2014-03-03 21:45
Peer-Review Started
2014-03-14 09:49
To Make the First Decision
2014-04-15 19:34
Return for Revision
2014-04-21 19:51
Revised
2014-05-05 12:54
Second Decision
2014-06-23 10:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-23 10:16
Articles in Press
2014-06-23 10:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-11-11 11:53
Publish the Manuscript Online
2014-11-20 20:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Effect of liver regeneration on malignant hepatic tumors
Manuscript Source Invited Manuscript
All Author List Ji-Hua Shi and Pål-Dag Line
Funding Agency and Grant Number
Corresponding Author P?l-Dag Line, MD PhD FEBS (Tx), Chairman, Department of Transplantation Medicine, Oslo University Hospital, Postboks 4950 Nydalen – 0424, Oslo, Norway E-mail: p.d.line@medisin.uio.no Tel: +47 23070509 Fax: +47 23070510
Key Words Hepatocellular carcinoma; Colorectal cancer; Recurrence; Liver regeneration; Hepatic progenitor cell; Epithelial to mesenchymal transition
Core Tip The liver has a unique capacity for regeneration after cellular damage or partial removal of tissue,and modern liver surgery relies on this property. Liver regeneration is a complex process involving a large array of growth factors, cytokines and cells to restore hepatic mass and function. Experimental and clinical data indicate that the regeneration signals facilitate the growth of both primary and secondary liver tumors and can alter their malignant potential. This is an important mechanism underlying recurrence after liver surgery. New therapeutic strategies founded on better insight into the relationship between liver regeneration and tumor biology are needed.
Publish Date 2014-11-20 20:51
Citation Shi JH, Line PD. Effect of liver regeneration on malignant hepatic tumors. World J Gastroenterol 2014; 20(43): 16167-16177
URL http://www.wjgnet.com/1007-9327/full/v20/i43/16167.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i43.16167
Full Article (PDF) WJG-20-16167.pdf
Full Article (Word) WJG-20-16167.doc
Manuscript File 9908-Review.docx
Answering Reviewers 9908-Answering reviewers.pdf
Copyright License Agreement 9908-Copyright assignment.pdf
Peer-review Report 9908-Peer review.pdf
Scientific Misconduct Check 9908-CorssCheck.jpg
Scientific Editor Work List 9908-Scientific editor work list.pdf