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Reader Comments
Publication Name
Article Title
Year Published
1
"It is well prepared and organised article. However they used an expensive metallic stent instead of a cheaper silicone tube. It can be better to discuss other choises and why they chose stent." 
Cheng SL, Xie L, Wu HW, Zhang XF, Lou LL, Shen HZ. Metal stent combined with ileus drainage tube for the treatment of delayed rectal perforation: A case report. World J Clin Cases 2022; 10(23): 8406-8416 [DOI: 10.12998/wjcc.v10.i23.8406]
2
"Can the method part be presented separately in METHODS? This is more clear and beneficial to readers." 
Rais K, El Eulj O, El Moutaoukil N, Kamaoui I, Bennani A, Kharrasse G, Zazour A, Khannoussi W, Ismaili Z. Solitary pancreatic metastasis from squamous cell lung carcinoma: A case report and review of literature. World J Gastrointest Endosc 2022; 14(7): 455-466 [DOI: 10.4253/wjge.v14.i7.455]
3
"Congratulations to the authors. They highlighted adequately the important role of imaging in diagnosis and the current management strategy of pancreaticobiliary maljunction. It is well known that the long common channel (10-20 mm in length) is a predisposing factor for both gall bladder and common bile duct cancer development in long term due to pancreatic fluid reflux into the extrahepatic biliary tree that causes by converting bile lecithin to lysolecithin, chronic irritation of biliary epithelium and finally carcinogenesis." 
Wang JY, Mu PY, Xu YK, Bai YY, Shen DH. Application of imaging techniques in pancreaticobiliary maljunction. World J Clin Cases 2022; 10(22): 7642-7652 [DOI: 10.12998/wjcc.v10.i22.7642]
4
"It is a well-written comprehensive opinion review on a serious condition of infected necrotizing pancreatitis presenting the current data. I agree absolutely with the proposed step-by-step management. I would like first to congratulate the authors and second to make clear that the on-time detection of sepsis is crucial. Despite the intensive care efforts, the ongoing deterioration of the clinical picture is a strong indication. It is depended on a quick SOFA score (at least two out of three clinical indications are present i.e. tachypnea ≥ 22/ min, low level of consciousness and arterial pressure ≤ 100 mm Hg). This score along with procalcitonin levels >1.8 ng/ml and increased lactates necessitates urgent operation including necrosectomy, peritoneal lavage and wide drainage, either open or laparoscopic. This management gives about a 50% chance of survival in otherwise condemned patients." 
Xiao NJ, Cui TT, Liu F, Li W. Invasive intervention timing for infected necrotizing pancreatitis: Late invasive intervention is not late for collection. World J Clin Cases 2022; 10(23): 8057-8062 [DOI: 10.12998/wjcc.v10.i23.8057]
5
"It is a narrative minireview article. For evidence-based synthesis in favour of beta-blocker in COVID-19, a meta-analysis or systematic review would have given a better insight." 
Santillo E, Migale M. Beta receptor blocker therapy for the elderly in the COVID-19 era. World J Clin Cases 2022; 10(23): 8088-8096 [DOI: 10.12998/wjcc.v10.i23.8088]
6
"It is a nice article. But it lacks an explanation of methodology and statistical analysis aspects, and discussion on preventive and rehabilitative aspects. What search strategy the authors used there is no such mention. Otherwise, it is an informative article." 
Dhaduk K, Khosla J, Hussain M, Mangaroliya V, Chauhan S, Ashish K, Gupta R, Pal S. COVID-19 vaccination and myocarditis: A review of current literature. World J Virol 2022; 11(4): 170-175 [DOI: 10.5501/wjv.v11.i4.170]
7
"Dear editor thank you for sharing this article we have carefully read the article and we would like to congratulate the authors for addressing an important aspect of diagnosing COVID-19 infection .ALL the scientific argument made in the article were sound and concise the advantage of RT-PCR over rapid antigen-detection tests are discussed well .The authors clearly argued the disadvantage of rapid antigen-detection tests in comparison to RT-PCR .However one must not forget the disadvantage of the latter test and its limitation that were intensively examined and addressed in many article ,a good example of these are published in RT- PCR, the gold standard in CoViD-19 diagnosis: the most common pitfalls and their interpretations https://www.oncology-and-cytogenetic-products.com/rt-pcr-the-gold-standard-in-covid-19-diagnosis-the-most-common-pitfalls-and-their-interpretations/ in this article the carful steps that one needs to follow in achieving the best accurate result and to avoid the pitfalls are well discussed, it could be a nice addition to the published article to cover the full aspects of the main research tool which is RT-PCR Best regrades " 
Tabain I, Cucevic D, Skreb N, Mrzljak A, Ferencak I, Hruskar Z, Misic A, Kuzle J, Skoda AM, Jankovic H, Vilibic-Cavlek T. Field evaluation of COVID-19 rapid antigen test: Are rapid antigen tests less reliable among the elderly? . World J Clin Cases 2022; 10(19): 6456-6463 [DOI: 10.12998/wjcc.v10.i19.6456]
8
"An interesting report." 
Tamam MO, Tamam MC. Artificial intelligence technologies in nuclear medicine. World J Radiol 2022; 14(6): 151-154 [DOI: 10.4329/wjr.v14.i6.151]
9
"correct argument" 
Wang JK, Wei W, Zhao DY, Wang HF, Zhang YL, Lei JP, Yao SK. Intestinal mucosal barrier in functional constipation: Dose it change? World J Clin Cases 2022; 10(19): 6385-6398 [DOI: 10.12998/wjcc.v10.i19.6385]
10
"A precise examination regarding eradication therapy of Helicobacter pylori n the East, which allows considerations in multiple directions" 
Cho JH, Jin SY. Current guidelines for Helicobacter pylori treatment in East Asia 2022: Differences among China, Japan, and South Korea. World J Clin Cases 2022; 10(19): 6349-6359 [DOI: 10.12998/wjcc.v10.i19.6349]
11
"The article follows current events and proposes a treatment for COVID-19 using stem cells." 
Cuevas-González MV, Cuevas-González JC. Stem cells as an option for the treatment of COVID-19. World J Clin Cases 2022; 10(18): 6338-6340 [PMID: 35949843 DOI: 10.12998/wjcc.v10.i18.6338]
12
"This paper is a novel attempt to summarize the treatment of diabetes at the level of genomics." 
Huang YY, Zhang XY, Zhu P, Ji L. Development of clustered regularly interspaced short palindromic repeats/CRISPR-associated technology for potential clinical applications. World J Clin Cases 2022; 10(18): 5934-5945 [PMID: 35949837 DOI: 10.12998/wjcc.v10.i18.5934]
13
"It is a nice review in a nutshell on hepatitis E-associated liver failure." 
Cho JH, Jin SY. Current guidelines for Helicobacter pylori treatment in East Asia 2022: Differences among China, Japan, and South Korea. World J Clin Cases 2022; 10(19): 6349-6359 [DOI: 10.12998/wjcc.v10.i19.6349]
14
"In this paper the authors used HAR as yet another measure to assess the prognosis of Gastric cancer. The authors clearly showed the usefulness of HAR in this regard. However, it would have been better if the authors included Hb and Albumin as independent parameters to predict prognosis along with the HAR data they have analyzed. Additionally, it would have been nice to mention whether other factors like UGI bleeding resulted in a low HB. Finally, what was the rationale for coming up with the HAR for this study." 
Hu CG, Hu BE, Zhu JF, Zhu ZM, Huang C. Prognostic significance of the preoperative hemoglobin to albumin ratio for the short-term survival of gastric cancer patients . World J Gastrointest Surg 2022; 14(6): 580-593 [DOI: 10.4240/wjgs.v14.i6.580]
15
"In order to describe the immunophenotype of immune checkpoint (IC) expression in OAC patients before and after radiotherapy, evaluate the effect of checkpoint blocking on cell viability, and pay more and more attention to the spread of anti-tumor immune response, this article studies the effect of radiation and checkpoint blocking on cell viability in OAC patients. A mixed combination of in vitro and in vitro models was used. The serum immune proteins were quantified by enzyme-linked immunosorbent assay. Flow cytometry staining was used to evaluate IC expression in OAC cell lines and OAC biopsies in vitro. The cell viability was evaluated by cell counting kit-8 analysis under the radiation conditions with or without IC blocking. The experimental process and data results are clear. The results of this study have great implications for clinical practice. In the new adjuvant treatment environment, ICIS and ionizing radiation have synergistic effects, which also have obvious implications for the treatment of specific patients in the future. It is a rare good article" 
Donlon NE, Davern M, O’Connell F, Sheppard A, Heeran A, Bhardwaj A, Butler C, Narayanasamy R, Donohoe C, Phelan JJ, Lynam-Lennon N, Dunne MR, Maher S, O’Sullivan J, Reynolds JV, Lysaght J. Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma. World J Gastroenterol 2022; 28(21): 2302-2319 [PMID: 35800186 DOI: 10.3748/wjg.v28.i21.2302]
16
"This review explores recent advances in biomarkers that may help identify clinically relevant PSC subgroups, assist in daily clinical work (e.g., diagnosis, disease stratification or monitoring) and explore potential therapeutic targets. Alkaline phosphatase produced by bile duct epithelial cells is associated with prognosis. In addition, this paper briefly reviews the evidence of these possible serological markers, which may help to solve the unmet clinical needs in PSC, from routine laboratory tests and comprehensive scores, immunoglobulins, other serological biomarkers, and the detection of serological biomarkers of cholangiocarcinoma in PSC. However, as mentioned in the article, the diagnosis of PSC is very difficult. So far, no specific biomarkers of the disease have been identified, and the problems of accurate risk assessment, disease stratification and follow-up strategy of PSC patients have not been solved. Some biomarkers can predict the prognosis of PSC, most of which have not been verified by subsequent studies. But the future clinical practice and research can open up a new way for medical treatment. This article is a very good and enlightening article worthy of continuous attention and reading" 
Tornai D, Ven PL, Lakatos PL, Papp M. Serological biomarkers for management of primary sclerosing cholangitis. World J Gastroenterol 2022; 28(21): 2291-2301 [PMID: 35800183 DOI: 10.3748/wjg.v28.i21.2291]
17
"This paper describes a systematic method of therapeutic drug monitoring (TDM) to manage these patients under the primary or secondary non response of biological agents and immunomodulators (IMM), summarizes the latest data of TDM, focuses on reactive TDM and active TDM, and discusses the effect of TDM on biological agents and thiopurines in the treatment of active IBD. It is analyzed from multiple drug perspectives, such as using research data and conclusions to evaluate the evolution over time and its correlation with clinical outcomes. It is revealed that TDM is helpful to predict the loss of response and prevent treatment failure. Higher serum drug concentration can improve the prognosis and reduce hospitalization, surgery and treatment failure. TDM plays an important role in the treatment outcome of IBD patients using biological agents. And TDM play an important role in the future clinical treatment. However, the use of TDM in IBD patients still has limitations. It is still necessary to further study the importance of different levels of ADA and analyze the correlation. Finally, it will be applied in the medical clinical environment." 
Lodhia N, Rao S. Updates in therapeutic drug monitoring in inflammatory bowel disease. World J Gastroenterol 2022; 28(21): 2282-2290 [PMID: 35800180 DOI: 10.3748/wjg.v28.i21.2282]
18
"This review recommends appropriate monitoring through clinical biochemical score and regular ultrasound evaluation, and summarizes the virus and microenvironment of disease occurrence, as well as the pathophysiology and molecular pathways of chronic infection and carcinogenesis of HBV, HCV and HDV, so as to clarify the mechanism of tumorigenesis, cooperate with the design of future treatment schemes for this kind of cancer, and focus on the impact of clinical monitoring and antiviral treatment on the risk of HCC. The detailed description is carried out from multiple angles of each virus. The diagram is clear and easy to understand, the data is real and detailed, and the research and design data are cited many times. Conclusion HBV and HCV infected patients have a higher risk of carcinogenesis, mainly because of the interaction between viral proteome, transcriptome and host cell molecular pathways, involving inflammation and cell replication. And looking forward to the future, the new biomarkers and risk stratification system may help clinicians identify patients for closer follow-up, so as to achieve more personalized liver cancer monitoring methods." 
Stella L, Santopaolo F, Gasbarrini A, Pompili M, Ponziani FR. Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment. World J Gastroenterol 2022; 28(21): 2251-2281 [PMID: 35800182 DOI: 10.3748/wjg.v28.i21.2251]
19
"So the ureteral obstrucion was a necrotic papillae? It seems a very rare entity to me, particularly, never seen it before. The ureteroscopy doesn't showed any other findings? Like distal ureteral stenosis maybe? Otherwise it is a very nice case, congratulations! " 
Pan HH, Luo YJ, Zhu QG, Ye LF. Renal papillary necrosis with urinary tract obstruction: A case report. World J Clin Cases 2022; 10(16): 5400-5405 [PMID: 35812662 DOI: 10.12998/wjcc.v10.i16.5400]
20
"I agreed with the author. Future study should be conducted in the form of clinical trial to confirm the finding especially in term of glycemic control benefit since single drug showed relatively better HbA1c reduction compared to combination of both drug. " 
Singh AK, Singh R. Metabolic and cardiovascular benefits with combination therapy of SGLT-2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. World J Cardiol 2022; 14(6): 329-342 [DOI: 10.4330/wjc.v14.i6.329]
21
"The study is considered an evolution with new athropometric measurement, AH which can be applied in clinical routine practice or in public. Probably bigger sample size of participant with prospective design of study will give strong support to encourage the health centre use this type of measurement (AH)." 
Sirisena A, Okeahialam B. Association of obesity anthropometric indices with hypertension, diabetes mellitus and hypertriglyceridemia in apparently healthy adult Nigerian population. World J Cardiol 2022; 14(6): 363-371 [DOI: 10.4330/wjc.v14.i6.363]
22
"We read with great interest the article entitled " Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases ". In this article, we detected several shortcomings that we present in our letter to the editor, anticipating a discussion with the authors" 
Akiyama S, Sakamoto T, Steinberg JM, Saito Y, Tsuchiya K. Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases. World J Gastrointest Oncol 2022; 14(3): 646-653 [PMID: 35321277 DOI: 10.4251/wjgo.v14.i3.646]
23
"Objectives were clear. And the results of the study for me is very beneficial to stimulate more work in producing better vaccine in the futre. However, the result of myocarditis incidence probably under reported especially those with mild or no symtom, do not report the very mild symptoms or some of them, there were overlapping between vaccination or covid 19 infection occured within similar time interval. " 
Leowattana W, Leowattana T. COVID-19 vaccination and cardiac dysfunction. World J Cardiol 2022; 14(6): 343-354 [DOI: 10.4330/wjc.v14.i6.343]
24
"We read with interest a questionnaire survey by Zhang YQ et al [1], who presented the Chinese population has limited knowledge of the initiative practice for health (IPFH). People with strong IPFH awareness are older, earn more, and have medical-related work experience. We agree with the author, that is, young people, the low-income populations, rural populations, And people with a low level of education may not be able to do Initiative Practice for Health, so it is particularly important for TCM to popularize science in disease prevention and health maintenance. Since the premise of active health practice is the awakening of health consciousness, how to improve health awareness is the key to the problem. As the premise of active health practice is the awakening of health consciousness, how to improve the health awareness of the people at the bottom is the key to the problem. For the less literate in India, dehyphenation campaigns, folk media and interpersonal communication have been effective [2]. In Saudi Arabia, the promotion of universal health education is restricted by religion and gender [3]. In China, which is also a developing country, nine-year compulsory education has been basically realized, there is less interference from external factors, and the unique TCM culture has been inherited for thousands of years in Chinese history. Therefore, it is a feasible strategy to give full play to the unique advantages of TCM [4]." 
Zhang YQ, Zhou MY, Jiang MY, Zhang XY, Wang X, Wang BG. Awareness of initiative practice for health in the Chinese population: A questionnaire survey based on a network platform. World J Clin Cases 2022; 10(16): 5241-5252 [PMID: 35812685 DOI: 10.12998/wjcc.v10.i16.5241]
25
"Since glutamine metabolism also affects cancer cell survival, it is likely to need more consideration." 
Wang W, Guo MN, Li N, Pang DQ, Wu JH. Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis. World J Gastrointest Oncol 2022; 14(6): 1124-1140 [PMID: 35949216 DOI: 10.4251/wjgo.v14.i6.1124]
26
"Dear Editor, We recently read with great interest the abovementioned article. Although we appreciate the venture of Najeeb H et al, based on our in-depth reading, we came across several shortcomings. All of our comments are enclosed in our submitted letter, anticipating discussion with the authors. Yours faithfully " 
Najeeb H, Yasmin F, Surani S. Emerging role of biosimilars in the clinical care of inflammatory bowel disease patients. World J Clin Cases 2022; 10(14): 4327-4333 [PMID: 35663066 DOI: 10.12998/wjcc.v10.i14.4327]
27
"It is dealing with the contents that can be considered for biosimilars as a possible option for IBD treatment. Very interesting." 
Najeeb H, Yasmin F, Surani S. Emerging role of biosimilars in the clinical care of inflammatory bowel disease patients. World J Clin Cases 2022; 10(14): 4327-4333 [PMID: 35663066 DOI: 10.12998/wjcc.v10.i14.4327]
28
"Interesting and uncommon topic. The manuscript is fluent and easy for the reader to read. The images are clear and well described. References often dated. The overall value of the manuscript is medium" 
Li XY, Teng G, Zhao X, Zhu CM. Primary sigmoid squamous cell carcinoma with liver metastasis: A case report. World J Clin Cases 2022; 10(14): 4608-4616 [PMID: 35663075 DOI: 10.12998/wjcc.v10.i14.4608]
29
"Various therapies targeting pancreatic neuroendocrine neoplasms have been well documented. It is very helpful as a reference for studying the PanNENs in a view of treatment." 
Li YL, Cheng ZX, Yu FH, Tian C, Tan HY. Advances in medical treatment for pancreatic neuroendocrine neoplasms. World J Gastroenterol 2022; 28(20): 2163-2175 [PMID: 35721885 DOI: 10.3748/wjg.v28.i20.2163]
30
"Basically, I agree with these results and I actually interpose omentum in PD, but the weak point of this paper is that it was retrospective fashion. As pancreatic fistula is less likely to occur in PDAC, the rate of PDAC (somewhat high in omental interposition even in PSM) might affect the results." 
Li Y, Liang Y, Deng Y, Cai ZW, Ma MJ, Wang LX, Liu M, Wang HW, Jiang CY. Application of omental interposition to reduce pancreatic fistula and related complications in pancreaticoduodenectomy: A propensity score-matched study. World J Gastrointest Surg 2022; 14(5): 482-493 [PMID: 35734624 DOI: 10.4240/wjgs.v14.i5.482]
31
" The author can elaborate it providing one pic, that will be more interesting for the readers" 
Yao S, Wei Y, Song B. Providing higher value care for hepatocellular carcinoma rather than diagnosis: What can current radiologists do? World J Gastrointest Surg 2022; 14(5): 525-527 [PMID: 35734617 DOI: 10.4240/wjgs.v14.i5.525]
32
"Comments from Huanjie Li (lihuanjie@sdu.edu.cn) Helicobacter pylori, the major risk factor of gastric cancer, is categorized as a class I carcinogen. Recently,an increasing evidence suggests that the GIT (gastrointestinal tract) microbiota, especially the gastric microbiota affects health and disease. However, the molecular mechanism of the relationship between H. pylori infection, gastric microbiota and gastric cancer (GC) remains unclear. Based on recent studies, Liatsos, et al. attempted to summarize the impact of different factors including Hp-I on gastric microbiota composition to unroll the tangle regarding the interaction between Hp-I, GM and GC. The review showed that the perpetuation of Hp-I reduces microbiota diversity and is connected with atrophy, IM and GC. H. pylori entirely dominated the microbiota not only in infected patients but also in the majority of individuals categorized as H. pylori-infected using conventional approaches, thus implying an active role in all cases of GC development. It is more than clear that Hp-I, GM and GC constitute a challenging tangle due to the strong interaction between them making it difficult to unroll it. Beyond H. pylori’s role in gastric oncogenesis, other bacteria, H. pylori-stimulated or not, in GM also seem to be responsible for transformation of gastric epithelial cells. The review suggested that the maze of GC complex pathogenesis where abundant data showed that beyond H. pylori related gastritis, additional pathogens might contribute to this type of cancer development. Nevertheless, large-scale experiments are needed to discern the exact role of different kinds of pathogens which reside in the stomach and their contribution to neoplasia emergence, aiding in the prediction of adverse prognosis of a specific microbiota diversity. The mechanisms of H. pylori infection, GM and GC relationship are critical for the early diagnosis and treatment of GC. " 
Liatsos C, Papaefthymiou A, Kyriakos N, Galanopoulos M, Doulberis M, Giakoumis M, Petridou E, Mavrogiannis C, Rokkas T, Kountouras J. Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle. World J Gastrointest Oncol 2022; 14(5): 959-972 [PMID: 35646287 DOI: 10.4251/wjgo.v14.i5.959]
33
"It is teaching that calcium supplementation on severe hypocalcemia in patients following secondary hyperparathyroidism after total parathyroidectomy is important. It gives an important implication in clincial." 
Liu J, Fan XF, Yang M, Huang LP, Zhang L. Effect of calcium supplementation on severe hypocalcemia in patients with secondary hyperparathyroidism after total parathyroidectomy. World J Clin Cases 2022; 10(13): 4033-4041 [PMID: 35665128 DOI: 10.12998/wjcc.v10.i13.4033]
34
"CT imaging seemed challenging to preserve the spleen, so the operation was done well. As for rareness, many doctors would like to see the intraoperative photos and resected specimen. Paragraph of TREATMENT should be before pathological findings. " 
Ha FS, Liu H, Han T, Song DZ. Primary hepatic angiosarcoma manifesting as hepatic sinusoidal obstruction syndrome: A case report. World J Gastrointest Oncol 2022; 14(5): 1050-1056 [PMID: 35646288 DOI: 10.4251/wjgo.v14.i5.1050]
35
" very interesting topic," 
Garbuzenko DV. Pathophysiological mechanisms of hepatic stellate cells activation in liver fibrosis . World J Clin Cases 2022; 10(12): 3662-3676 [PMID: 35647163 DOI: 10.12998/wjcc.v10.i12.3662]
36
"Good" 
Zhang CC, Chen P. Anti-programmed death 1 antibody in the treatment of coexistent Mycobacterium fortuitum and lung cancer: A case report. World J Clin Cases 2022; 10(12): 3801-3807 [PMID: 35647142 DOI: 10.12998/wjcc.v10.i12.3801]
37
"Authors made that the scientific community gradually realized the importance of the impact of IOL tilt and decentration on their quantification and the precision improvement of measurement methods. The usage of multifocal IOLs (MIOLs) and extended depth of focus (EDOF) IOLs is significantly higher than that in the past owing to the improvement in the quality of life. And it is necessary to clearly identify the causes of IOL tilt and decentration and their effects on the postoperative visual quality of different IOL eyes, especially trifocal and EDOF IOL eyes, guidance for selecting a proper IOL and determine the effective lens position for improving the postoperative visual effect of cataract patient was attempted to provide it. " 
Chen XY, Wang YC, Zhao TY, Wang ZZ, Wang W. Tilt and decentration with various intraocular lenses: A narrative review. World J Clin Cases 2022; 10(12): 3639-3646 [PMID: 35647149 DOI: 10.12998/wjcc.v10.i12.3639]
38
"This is an interesting mini review. The prognostic impact of FIB-4, APRI etc was not mentioned" 
Elnaggar M, Abomhya A, Elkhattib I, Dawoud N, Doshi R. COVID-19 and liver diseases, what we know so far. World J Clin Cases 2022; 10(13): 3969-3980 [PMID: 35665122 DOI: 10.12998/wjcc.v10.i13.3969]
39
"good" 
He T, Liu C, Lu ZX, Kong LL, Li Y, Xu Z, Dong YJ, Hao W. Effect of wrist-ankle acupuncture on propofol dosage during painless colonoscopy: A randomized controlled prospective study. World J Clin Cases 2022; 10(12): 3764-3772 [PMID: 35647164 DOI: 10.12998/wjcc.v10.i12.3764]
40
"good" 
Shi YC, Li J, Li SJ, Li ZP, Zhang HJ, Wu ZY, Wu ZY. Flap failure prediction in microvascular tissue reconstruction using machine learning algorithms. World J Clin Cases 2022; 10(12): 3729-3738 [PMID: 35647170 DOI: 10.12998/wjcc.v10.i12.3729]
41
"good" 
Ding F, Chen RY, Hou J, Guo J, Dong TY. Efficacy and prognostic factors of neoadjuvant chemotherapy for triple-negative breast cancer. World J Clin Cases 2022; 10(12): 3698-3708 [PMID: 35647172 DOI: 10.12998/wjcc.v10.i12.3698]
42
"good" 
Garbuzenko DV. Pathophysiological mechanisms of hepatic stellate cells activation in liver fibrosis . World J Clin Cases 2022; 10(12): 3662-3676 [PMID: 35647163 DOI: 10.12998/wjcc.v10.i12.3662]
43
"good" 
Chen XY, Wang YC, Zhao TY, Wang ZZ, Wang W. Tilt and decentration with various intraocular lenses: A narrative review. World J Clin Cases 2022; 10(12): 3639-3646 [PMID: 35647149 DOI: 10.12998/wjcc.v10.i12.3639]
44
"Good" 
Li ZP, Xu DH, He LP, Wang XJ. Fuzhuan brick tea affects obesity process by modulating gut microbiota. World J Gastrointest Pharmacol Ther 2022; 13(3): 30-32 [PMID: 35646421 DOI: 10.4292/wjgpt.v13.i3.30]
45
"This is an interesting paper but in small cohort. FIB-4 was not included in multi analysis. The latter should be COX providing HR and not OR" 
Madian A, Eliwa A, Abdalla H, A Azeem Aly H. Aspartate transferase-to-platelet ratio index-plus: A new simplified model for predicting the risk of mortality among patients with COVID-19. World J Gastroenterol 2022; 28(16): 1671-1680 [PMID: 35581967 DOI: 10.3748/wjg.v28.i16.1671]
46
"This review summarizes the state-of-the-art artificial intelligence( AI) in the endoscopic diagnosis and treatment of biliary diseases. It is a well-written and useful article. However, almost all AI-related articles are retrospective studies. Prospective studies are desirable in the future in this field of study. " 
Correia FP, Lourenço LC. Artificial intelligence in the endoscopic approach of biliary tract diseases: A current review. Artif Intell Gastrointest Endosc 2022; 3(2): 9-15 [DOI: 10.37126/aige.v3.i2.9]
47
"We know the dietary intervention a little more specific to the SARS-CoV-2 virus infection. References: PMID: 35126592 by Ikeda et al, and PMID: 33042496 by murakami et al." 
Wang MK, Yu XL, Zhou LY, Si HM, Hui JF, Hou DY, Li WP, Yang JS. COVID-19 and liver dysfunction: What nutritionists need to know. World J Gastroenterol 2022; 28(15): 1526-1535 [PMID: 35582132 DOI: 10.3748/wjg.v28.i15.1526]
48
"It was possible to estimate the therapeutic potential of immunotherapy targeting colorectal cancer, classified as a cold tumor. Very interesting." 
Xu YJ, Zhang P, Hu JL, Liang H, Zhu YY, Cui Y, Niu P, Xu M, Liu MY. Regorafenib combined with programmed cell death-1 inhibitor against refractory colorectal cancer and the platelet-to-lymphocyte ratio’s prediction on effectiveness. World J Gastrointest Oncol 2022; 14(4): 920-934 [PMID: 35582108 DOI: 10.4251/wjgo.v14.i4.920]
49
"Information on the vasoactive intestinal peptide secreting tumour is well documented. Very helpful." 
Una Cidon E. Vasoactive intestinal peptide secreting tumour: An overview. World J Gastrointest Oncol 2022; 14(4): 808-819 [PMID: 35582098 DOI: 10.4251/wjgo.v14.i4.808]
50
"Very interesting and innovative topic. The review, although very long, is pleasant to read, complete, well organized and offers a complete picture of the subject. There are many references and well organized." 
Christou CD, Tsoulfas G. Role of three-dimensional printing and artificial intelligence in the management of hepatocellular carcinoma: Challenges and opportunities. World J Gastrointest Oncol 2022; 14(4): 765-793 [PMID: 35582107 DOI: 10.4251/wjgo.v14.i4.765]