ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Radiology, Nuclear Medicine & Medical Imaging |
Manuscript Type |
Basic Study |
Article Title |
Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hye Rim Cho, Youkyung Lee, Philip Doble, David Bishop, Dominic Hare, Young-Jae Kim, Kwang Gi Kim, Hye Seung Jung, Kyong Soo Park, Seung Hong Choi and Woo Kyung Moon |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Innovative Research Institute for Cell Therapy, Ministry for Health, Welfare and Family Affairs in South Korea |
A062260 |
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Corresponding Author |
Seung Hong Choi, MD, PhD, Department of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul 110-744, South Korea. verocay@snuh.org |
Key Words |
Gadofluorine P; Gd-DOTA; Magnetic resonance contrast media; Type 1 diabetes; Pancreas |
Core Tip |
Early changes in type 1 diabetes involve islet microvasculature such that vascular permeability increases. We used noninvasive magnetic resonance imaging to image, in vivo, the vasculature of the pancreas in streptozotocin-induced diabetic rats using Gadofluorine P. We anticipate that with further development, this technique could diagnose type 1 diabetes early, as well as monitor vascular and islet changes noninvasively and quantitatively. |
Publish Date |
2015-05-20 17:01 |
Citation |
Cho HR, Lee Y, Doble P, Bishop D, Hare D, Kim YJ, Kim KG, Jung HS, Park KS, Choi SH, Moon WK. Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA. World J Gastroenterol 2015; 21(19): 5831-5842 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i19/5831.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i19.5831 |