| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Clinical characteristics and prognostic impact of atrial fibrillation in patients with chronic heart failure
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Lorenzo Gigli, Pietro Ameri, Gianmarco Secco, Gabriele De Blasi, Roberta Miceli, Alessandra Lorenzoni, Francesco Torre, Francesco Chiarella, Claudio Brunelli and Marco Canepa |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Marco Canepa, MD, PhD, Assistant Professor of Cardiology, Cardiovascular Disease Unit, Department of Internal Medicine, University of Genova and IRCCS Azienda Ospedaliera Universitaria San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, 10, 16132 Genova,
Italy. marco.canepa@unige.it
|
| Key Words |
Atrial fibrillation; Chronic heart failure; Beta-blockers; Digoxin; Prognosis |
| Core Tip |
In this retrospective analysis atrial fibrillation (AF) was diagnosed in 1 out of 5 patients with chronic heart failure. The arrhythmia was associated with older age, worse clinical presentation and underutilization of disease-modifying medications, particularly beta-blockers (BB) and ACE inhibitors/angiotensin receptor blockers. At a mean follow-up of about 5 years, mortality was significantly higher in patients with AF, and patients with AF not receiving BB treatment were found to have the worst prognosis. However, in a multivariate analysis including main significant predictors of all-cause mortality, such as age, gender, blood pressure, coronary artery disease, comorbidities and medications, the univariate relationship between AF and death became not statistically significant.
|
| Publish Date |
2016-11-24 18:18 |
| Citation |
Gigli L, Ameri P, Secco G, De Blasi G, Miceli R, Lorenzoni A, Torre F, Chiarella F, Brunelli C, Canepa M. Clinical characteristics and prognostic impact of atrial fibrillation in patients with chronic heart failure. World J Cardiol 2016; 8(11): 647-656 |
| URL |
http://www.wjgnet.com/1949-8462/full/v8/i11/647.htm |
| DOI |
http://dx.doi.org/10.4330/wjc.v8.i11.647 |
