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Articles Published Processes
5/28/2018 9:41:37 AM | Browse: 952 | Download: 1247
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Received |
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2018-02-28 06:56 |
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Peer-Review Started |
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2018-02-28 07:29 |
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To Make the First Decision |
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2018-03-14 00:39 |
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Return for Revision |
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2018-03-15 05:57 |
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Revised |
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2018-03-21 06:14 |
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Second Decision |
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2018-04-13 08:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-04-15 23:19 |
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Articles in Press |
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2018-04-15 23:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-05-14 21:26 |
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Typeset the Manuscript |
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2018-05-18 06:05 |
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Publish the Manuscript Online |
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2018-05-28 09:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Juan Ma, Xing Wang, Wen-Ting Yan, Zhong-Guo Zhou, Zhi-Zhong Pan, Gong Chen and Rong-Xin Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81502459 |
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| Corresponding Author |
Rong-Xin Zhang, MD, Attending Doctor, Department of Colorectal Surgery, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Dongfeng East Road No. 651, Guangzhou 510060, Guangdong Province, China. zhangrx@sysucc.org.cn |
| Key Words |
Colorectal cancer; Indoleamine-2,3-dioxygenase 1; Cyclooxygenase-2; Prognosis |
| Core Tip |
It was reported that indoleamine-2,3-dioxygenase 1 (IDO1) is an inhibitory factor that suppresses the T cell response to tumors. In this study, we evaluated IDO1/cyclooxygenase 2 (COX2) expression as an independent prognostic biomarker for colorectal cancer (CRC) patients. In our multivariate Cox model, high coexpression of cytoplasmic IDO1/COX2 was found to be an independent predictor of poor outcome in CRC patients and celecoxib subgroup patients. Our results showed that cytoplasmic IDO1/COX2 coexpression could be used as an independent predictor for poor overall survival in CRC. |
| Publish Date |
2018-05-28 09:41 |
| Citation |
Ma WJ, Wang X, Yan WT, Zhou ZG, Pan ZZ, Chen G, Zhang RX. Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer. World J Gastroenterol 2018; 24(20): 2181-2190 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i20/2181.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i20.2181 |
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