ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Research & Experimental Medicine |
Manuscript Type |
Basic Study |
Article Title |
Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Dan Zhang, Yan-Bo Ren, Kai Wei, Jue Hong, Yan-Ting Yang, Li-Jie Wu, Ji Zhang, Zheng Shi, Huan-Gan wu and Xiao-Peng Ma |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81674073, 81202754, 81273843 |
National Key Basic Research Program of China |
2015CB554501, 2009CB522900 |
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Corresponding Author |
Xiao-Peng Ma, PhD, Professor, Laboratory of Acupuncture-moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, No. 650 South Wanping Road, Xuhui District, Shanghai 200030, China. pengpengma@163.com |
Key Words |
Cytokine expression profile; Ulcerative colitis; Protein microarray; Rats; Herb-partitioned moxibustion |
Core Tip |
Herb-partitioned moxibustion (HPM) has been shown to be effective in treating ulcerative colitis (UC) in recent years as a non-drug external therapy. In this study, we observed its effect on the expression profile of cytokines in UC rat colon. By protein functional cluster analysis and KEGG pathway analysis, we can conclude that the effect of HPM in promoting the repair of colon injuries of UC rats is plausibly related to the regulation of multiple abnormally-expressed cytokines, and the regulation of the signal pathways interacting between the cytokines and their receptors may be its significant immunological mechanism. |
Publish Date |
2018-08-13 07:45 |
Citation |
Zhang D, Ren YB, Wei K, Hong J, Yang YT, Wu LJ, Zhang J, Shi Z, Wu HG, Ma XP. Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats. World J Gastroenterol 2018; 24(30): 3384-3397 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i30/3384.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i30.3384 |